rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
C
0.730
CausalMutation
CLINVAR
Different RET gene mutation-induced multiple endocrine neoplasia type 2A in 3 Chinese families.
28099363
2017
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
0.730
GeneticVariation
BEFREE
The present study identified the clinical features of the largest multiple endocrine neoplasia type 2 (MEN2) A pedigree from China, with a novel double missense <i>rearranged during transfection (RET)</i> mutation (C634Y /D707E).
28943896
2017
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
Prophylactic thyroidectomy for asymptomatic 3-year-old boy with positive multiple endocrine neoplasia type 2A mutation (codon 634).
24684035
2015
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
High Discrepancy of Driver Mutations in Patients with NSCLC and Synchronous Multiple Lung Ground-Glass Nodules.
25629635
2015
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
Molecular diagnosis and comprehensive treatment of multiple endocrine neoplasia type 2 in Southeastern Chinese.
25628771
2015
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
Twenty years of lesson learning: how does the RET genetic screening test impact the clinical management of medullary thyroid cancer?
25440022
2015
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
C
0.730
CausalMutation
CLINVAR
RET mutations in a large indian family with medullary thyroid carcinoma.
25143909
2014
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
Characterization of wild-type and mutated RET proto- oncogene associated with familial medullary thyroid cancer.
24716929
2014
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.730
CausalMutation
CLINVAR
Comprehensive analysis of RET gene should be performed in patients with multiple endocrine neoplasia type 2 (MEN 2 ) syndrome and no apparent genotype-phenotype correlation : an appraisal of p.Y791F and p.C634Y RET mutations in five unrelated Brazilian families.
23723040
2013
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
0.730
GeneticVariation
BEFREE
Comprehensive analysis of RET gene should be performed in patients with multiple endocrine neoplasia type 2 (MEN 2 ) syndrome and no apparent genotype-phenotype correlation : an appraisal of p.Y791F and p.C634Y RET mutations in five unrelated Brazilian families.
23723040
2013
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.730
CausalMutation
CLINVAR
Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma.
21765987
2011
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma.
21765987
2011
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
Coincidence of multiple endocrine neoplasia type 2A with acromegaly.
20739875
2010
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
0.730
GeneticVariation
BEFREE
Three different known RET germline mutations in exon 11 (codon 634), p.Cys634Arg (c1900 T-->C) (de novo case), p.Cys634Phe (c1901 G-->T), p.Cys634Trp (c1902 C-->G), were detected in three individuals with MEN2 phenotype.
19841562
2010
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.730
CausalMutation
CLINVAR
Medullary thyroid carcinoma identified within the first year of life in children with hereditary multiple endocrine neoplasia type 2A (codon 634) and 2B.
19240193
2009
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
C
0.730
CausalMutation
CLINVAR
Familial prevalence and age of RET germline mutations: implications for screening.
18062802
2008
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
RET genetic screening in patients with medullary thyroid cancer and their relatives: experience with 807 individuals at one center.
17895320
2007
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.730
CausalMutation
CLINVAR
Pheochromocytoma penetrance varies by RET mutation in MEN 2A.
18063059
2007
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
Genotype-phenotype correlations in Hungarian patients with hereditary medullary thyroid cancer.
16865647
2006
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal.
16712668
2006
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
Clinical and biochemical features of sporadic and hereditary phaeochromocytomas: an analysis of 41 cases investigated in a single endocrine centre.
15452453
2004
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
C
0.730
CausalMutation
CLINVAR
The oncogenic activity of RET point mutants for follicular thyroid cells may account for the occurrence of papillary thyroid carcinoma in patients affected by familial medullary thyroid carcinoma.
15277225
2004
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
T
0.730
CausalMutation
CLINVAR
RET oncogene mutations in medullary thyroid carcinoma in Mexican families.
12604374
2004
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.730
CausalMutation
CLINVAR
RET oncogene mutations in medullary thyroid carcinoma in Mexican families.
12604374
2004
rs75996173
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Multiple endocrine neoplasia Type 2
A
0.730
CausalMutation
CLINVAR
Acceptable age for prophylactic surgery in children with multiple endocrine neoplasia type 2a.
12711285
2003