RORA, RAR related orphan receptor A, 6095

N. diseases: 10; N. variants: 36
Source: CURATED ×
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11071559
rs11071559
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0004096
Disease:
Asthma 		C 0.820 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
dbSNP: rs11071559
rs11071559
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0004096
Disease:
Asthma 		C 0.820 GeneticVariation GWASCAT Identification of a new locus at 16q12 associated with time to asthma onset. 27130862 2016
dbSNP: rs11071559
rs11071559
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0004096
Disease:
Asthma 		0.820 GeneticVariation GWASDB Genome-wide association study to identify genetic determinants of severe asthma. 22561531 2012
dbSNP: rs11071559
rs11071559
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0004096
Disease:
Asthma 		0.820 GeneticVariation GWASDB Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864 2011
dbSNP: rs11071559
rs11071559
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0004096
Disease:
Asthma 		C 0.820 GeneticVariation GWASDB A large-scale, consortium-based genomewide association study of asthma. 20860503 2010
dbSNP: rs11071559
rs11071559
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0004096
Disease:
Asthma 		C 0.820 GeneticVariation GWASCAT A large-scale, consortium-based genomewide association study of asthma. 20860503 2010
dbSNP: rs340005
rs340005
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C1278049
Disease:
Serum gamma-glutamyl transferase measurement 		0.800 GeneticVariation GWASCAT Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers. 30589442 2019
dbSNP: rs3743266
rs3743266
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C1314691
Disease:
Age at menarche 		0.800 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs339969
rs339969
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C1278049
Disease:
Serum gamma-glutamyl transferase measurement 		0.800 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs3743266
rs3743266
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C1314691
Disease:
Age at menarche 		T 0.800 GeneticVariation GWASCAT Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. 25231870 2014
dbSNP: rs340005
rs340005
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C1278049
Disease:
Serum gamma-glutamyl transferase measurement 		G 0.800 GeneticVariation GWASDB Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations. 22010049 2012
dbSNP: rs340005
rs340005
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C1278049
Disease:
Serum gamma-glutamyl transferase measurement 		G 0.800 GeneticVariation GWASCAT Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations. 22010049 2012
dbSNP: rs339969
rs339969
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C1278049
Disease:
Serum gamma-glutamyl transferase measurement 		A 0.800 GeneticVariation GWASCAT Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. 22001757 2011
dbSNP: rs339969
rs339969
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C1278049
Disease:
Serum gamma-glutamyl transferase measurement 		A 0.800 GeneticVariation GWASDB Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. 22001757 2011
dbSNP: rs340029
rs340029
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C0201657
Disease:
C-reactive protein measurement 		T 0.800 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. 21300955 2011
dbSNP: rs340029
rs340029
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C0201657
Disease:
C-reactive protein measurement 		T 0.800 GeneticVariation GWASDB Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. 21300955 2011
dbSNP: rs3743266
rs3743266
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C1314691
Disease:
Age at menarche 		C 0.800 GeneticVariation GWASCAT Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. 21102462 2010
dbSNP: rs3743266
rs3743266
Entrez Id: 6095;101928784
Gene Symbol: RORA;RORA-AS1
RORA;RORA-AS1
CUI: C1314691
Disease:
Age at menarche 		C 0.800 GeneticVariation GWASDB Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. 21102462 2010
dbSNP: rs8042149
rs8042149
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0038436
Disease:
Post-Traumatic Stress Disorder 		0.720 GeneticVariation GWASDB A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus. 22869035 2013
dbSNP: rs4775319
rs4775319
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0278996
Disease:
Malignant Head and Neck Neoplasm 		G 0.710 GeneticVariation GWASCAT We identified four common SNPs representing four genomic regions: 7q22.3 (rs10950641; SNX8; P = 3.39 × 10<sup>-14</sup>), 19p13.2 (rs4804217; PCP2; P = 2.95 × 10<sup>-9</sup>), 3q27.3 (rs6796803; KNG1; P = 6.42 × 10<sup>-9</sup>) and 15q22.2 (rs4775319; RORA; P = 1.02 × 10<sup>-8</sup>), suggesting SNX8, PCP2, KNG1 and RORA might be novel target genes for NP in patients with head and neck cancer. 29884837 2018
dbSNP: rs10519067
rs10519067
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0004096
Disease:
Asthma 		G 0.700 GeneticVariation GWASCAT Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. 30787307 2019
dbSNP: rs10519068
rs10519068
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0004096
Disease:
Asthma 		G 0.700 GeneticVariation GWASCAT Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. 30552067 2019
dbSNP: rs10519068
rs10519068
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0013595
Disease:
Eczema 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs11071559
rs11071559
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs11071559
rs11071559
Entrez Id: 6095
Gene Symbol: RORA
RORA
CUI: C0264408
Disease:
Childhood asthma 		0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019