RPS6KB1, ribosomal protein S6 kinase B1, 6198

N. diseases: 169; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs180515
rs180515
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0026769
Disease:
Multiple Sclerosis 		0.820 GeneticVariation BEFREE In the present study, we examined the association between two SNPs in RPS6KB1 (rs180515) and CD86 (rs9282641) with MS in Iranian population. 28079472 2017
dbSNP: rs180515
rs180515
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0026769
Disease:
Multiple Sclerosis 		0.820 GeneticVariation BEFREE All five tested single nucleotide polymorphisms showed consistent and statistically significant evidence for association with multiple sclerosis in our validation data sets (rs228614: odds ratio = 0.91, P = 2.4 × 10(-6); rs630923: odds ratio = 0.89, P = 1.2 × 10(-4); rs2744148: odds ratio = 1.14, P = 1.8 × 10(-6); rs180515: odds ratio = 1.12, P = 5.2 × 10(-7); rs6062314: odds ratio = 0.90, P = 4.3 × 10(-3)). 23739915 2013
dbSNP: rs180515
rs180515
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0026769
Disease:
Multiple Sclerosis 		G 0.820 GeneticVariation GWASCAT Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
dbSNP: rs180515
rs180515
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0026769
Disease:
Multiple Sclerosis 		G 0.820 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
dbSNP: rs1292034
rs1292034
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		0.700 GeneticVariation GWASCAT Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. 31407831 2019
dbSNP: rs1292034
rs1292034
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0855095
Disease:
Small Lymphocytic Lymphoma 		0.700 GeneticVariation GWASCAT Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. 31407831 2019
dbSNP: rs1292034
rs1292034
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0026769
Disease:
Multiple Sclerosis 		0.700 GeneticVariation GWASCAT Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. 31407831 2019
dbSNP: rs1051424
rs1051424
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0202236
Disease:
Triglycerides measurement 		A 0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs1292035
rs1292035
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0009324
Disease:
Ulcerative Colitis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs1292035
rs1292035
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0033860
Disease:
Psoriasis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs1292035
rs1292035
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0010346
Disease:
Crohn Disease 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs1292035
rs1292035
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0008313
Disease:
Cholangitis, Sclerosing 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs1292035
rs1292035
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0038013
Disease:
Ankylosing spondylitis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs1051424
rs1051424
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.010 GeneticVariation BEFREE Additional <i>in silico</i> analysis provided evidence that rs1051424 and rs11704 affect <i>RPS6KB1</i> and <i>ZNF839</i> expressions, which in turn is significantly correlated with prognosis in colorectal cancer. 28138309 2017
dbSNP: rs1051424
rs1051424
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C4722085
Disease:
Malignant neoplasm of colon and/or rectum 		0.010 GeneticVariation BEFREE Additional <i>in silico</i> analysis provided evidence that rs1051424 and rs11704 affect <i>RPS6KB1</i> and <i>ZNF839</i> expressions, which in turn is significantly correlated with prognosis in colorectal cancer. 28138309 2017