BDNF, brain derived neurotrophic factor, 627

N. diseases: 992; N. variants: 56
Disease: Alcoholic Intoxication, Chronic ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6265
rs6265
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.100 GeneticVariation BEFREE We found the BDNF Val66Met to be associated with alcohol dependence (p = 0.004). 29357295 2018
dbSNP: rs6265
rs6265
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.100 GeneticVariation BEFREE Haplotype analysis revealed the rs6265-rs7103411 A/C haplotype is associated with comorbid alcohol dependence</span> (P = 0.002). 24993285 2015
dbSNP: rs6265
rs6265
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.100 GeneticVariation BEFREE This study indicates a possible effect of BDNF Val66Met on alcohol addiction-related phenotypes in adolescence. 25650137 2015
dbSNP: rs6265
rs6265
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.100 GeneticVariation BEFREE These results suggest that the BDNF Val66Met polymorphism may contribute to alcohol dependence vulnerability via lower EFs performance. 23582695 2013
dbSNP: rs6265
rs6265
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.100 GeneticVariation BEFREE In conclusion, these data do not support the view that BDNF Val66Met polymorphism correlates with the specific alcohol related phenotypes in ethnically homogenous medication-free Caucasian subjects with alcohol dependence. 23023098 2013
dbSNP: rs6265
rs6265
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.100 GeneticVariation BEFREE An association between the BDNF Val66Met gene polymorphism and alcoholism was not found. 21098877 2011
dbSNP: rs6265
rs6265
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.100 GeneticVariation BEFREE Here, we investigated the possible association between three single nucleotide polymorphisms (SNPs) of the BDNF gene (rs13306221, rs6265, rs16917204) and AD-D. Of 548 patients with alcohol dependence (AD), 166 had AD-D and 312 healthy controls. 21880305 2011
dbSNP: rs6265
rs6265
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.100 GeneticVariation BEFREE The BDNF polymorphism Val66Met (rs6265) has been studied in the context of etiology of mental diseases including alcoholism. 21640793 2011
dbSNP: rs6265
rs6265
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.100 GeneticVariation BEFREE The Val66Met BDNF gene polymorphism was associated with a higher risk and earlier occurrence of relapse among patients treated for alcohol dependence. 19170664 2009
dbSNP: rs6265
rs6265
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.100 GeneticVariation BEFREE A study of the association of (Val66Met) polymorphism in the brain-derived neurotrophic factor gene with alcohol dependence and extreme violence in Chinese males. 15896496 2005
dbSNP: rs759834365
rs759834365
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.080 GeneticVariation BEFREE We found the BDNF Val66Met to be associated with alcohol dependence (p = 0.004). 29357295 2018
dbSNP: rs759834365
rs759834365
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.080 GeneticVariation BEFREE This study indicates a possible effect of BDNF Val66Met on alcohol addiction-related phenotypes in adolescence. 25650137 2015
dbSNP: rs759834365
rs759834365
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.080 GeneticVariation BEFREE In conclusion, these data do not support the view that BDNF Val66Met polymorphism correlates with the specific alcohol related phenotypes in ethnically homogenous medication-free Caucasian subjects with alcohol dependence. 23023098 2013
dbSNP: rs759834365
rs759834365
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.080 GeneticVariation BEFREE These results suggest that the BDNF Val66Met polymorphism may contribute to alcohol dependence vulnerability via lower EFs performance. 23582695 2013
dbSNP: rs759834365
rs759834365
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.080 GeneticVariation BEFREE An association between the BDNF Val66Met gene polymorphism and alcoholism was not found. 21098877 2011
dbSNP: rs759834365
rs759834365
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.080 GeneticVariation BEFREE The BDNF polymorphism Val66Met (rs6265) has been studied in the context of etiology of mental diseases including alcoholism. 21640793 2011
dbSNP: rs759834365
rs759834365
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.080 GeneticVariation BEFREE The Val66Met BDNF gene polymorphism was associated with a higher risk and earlier occurrence of relapse among patients treated for alcohol dependence. 19170664 2009
dbSNP: rs759834365
rs759834365
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.080 GeneticVariation BEFREE A study of the association of (Val66Met) polymorphism in the brain-derived neurotrophic factor gene with alcohol dependence and extreme violence in Chinese males. 15896496 2005
dbSNP: rs7103411
rs7103411
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.020 GeneticVariation BEFREE Haplotype analysis revealed the rs6265-rs7103411 A/C haplotype is associated with comorbid alcohol dependence</span> (P = 0.002). 24993285 2015
dbSNP: rs7103411
rs7103411
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.020 GeneticVariation BEFREE We further found that the G-G haplotype (rs4923463-rs2049045) (adjusted p=0.029) and the G-T haplotype (rs4923463-rs7103411) (adjusted p=0.029) were significantly more frequent in the group with alcoholism co-morbidity when compared with the group without this co-morbidity. 21167606 2011
dbSNP: rs2049045
rs2049045
Entrez Id: 627;497258
Gene Symbol: BDNF;BDNF-AS
BDNF;BDNF-AS
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.010 GeneticVariation BEFREE We further found that the G-G haplotype (rs4923463-rs2049045) (adjusted p=0.029) and the G-T haplotype (rs4923463-rs7103411) (adjusted p=0.029) were significantly more frequent in the group with alcoholism co-morbidity when compared with the group without this co-morbidity. 21167606 2011