THADA, THADA armadillo repeat containing, 63892

N. diseases: 47; N. variants: 49
Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7578597
rs7578597
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.840 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590 2017
dbSNP: rs7578597
rs7578597
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.840 GeneticVariation GWASDB Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 23300278 2013
dbSNP: rs7578597
rs7578597
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.840 GeneticVariation BEFREE To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we genotyped 1279 Japanese subjects (556 men and 723 women), who underwent computed tomography for measurements of visceral fat area (VFA) and subcutaneous fat area (SFA) for the following single-nucleotide polymorphisms (SNPs): NOTCH2 rs10923931, THADA rs7578597, PPARG rs1801282, ADAMTS9 rs4607103, IGF2BP2 rs1470579, VEGFA rs9472138, JAZF1 rs864745, CDKN2A/CDKN2B rs564398 and rs10811661, HHEX rs1111875 and rs5015480, TCF7L2 rs7901695, KCNQ1 rs2237892, KCNJ11 rs5215 and rs5219, EXT2 rs1113132, rs11037909, and rs3740878, MTNR1B rs10830963, DCD rs1153188, TSPAN8/LGR5 rs7961581, and FTO rs8050136 and rs9939609. 22377712 2012
dbSNP: rs7578597
rs7578597
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.840 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. 22325160 2012
dbSNP: rs7578597
rs7578597
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.840 GeneticVariation BEFREE THADA variant (rs7578597) was associated with type 2 diabetes (OR 1.5; 95% CI 1.04, 2.22; p = 0.03). 22052079 2012
dbSNP: rs7578597
rs7578597
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.840 GeneticVariation BEFREE Four type 2 diabetes SNPs were associated with colorectal cancer risk: rs7578597 (THADA), rs864745 (JAZF1), rs5219 (KCNJ11) and rs7961581 (TSPAN8, LGR5). 21602532 2011
dbSNP: rs7578597
rs7578597
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.840 GeneticVariation GWASDB Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. 21647700 2011
dbSNP: rs7578597
rs7578597
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.840 GeneticVariation BEFREE None of the variants was associated with T2D, but the meta-analysis of both cohorts revealed a modest trend of association of rs7578597 in THADA with T2D (p=0.055). 19670153 2010
dbSNP: rs7578597
rs7578597
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		T 0.840 GeneticVariation GWASDB Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. 18372903 2008
dbSNP: rs7578597
rs7578597
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		T 0.840 GeneticVariation GWASCAT Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. 18372903 2008
dbSNP: rs10203174
rs10203174
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.800 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922 2012
dbSNP: rs10203174
rs10203174
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.800 GeneticVariation GWASCAT Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922 2012
dbSNP: rs13414381
rs13414381
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs17334919
rs17334919
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		T 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458 2018
dbSNP: rs35720761
rs35720761
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.700 GeneticVariation GWASCAT Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. 29632382 2018
dbSNP: rs6743071
rs6743071
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		T 0.700 GeneticVariation GWASCAT Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. 29358691 2018
dbSNP: rs11899863
rs11899863
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922 2012
dbSNP: rs13405158
rs13405158
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		T 0.700 GeneticVariation GWASCAT Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922 2012