rs7652177
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Body Height
0.700
GeneticVariation
GWASCAT
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
20881960
2010
rs7652177
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Height
0.700
GeneticVariation
GWASDB
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
20881960
2010
rs4894535
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Corneal Topography
T
0.800
GeneticVariation
GWASCAT
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
23291589
2013
rs4894535
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Corneal Topography
T
0.800
GeneticVariation
GWASDB
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
23291589
2013
rs9647379
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
heart rate
C
0.800
GeneticVariation
GWASCAT
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
23583979
2013
rs9647379
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
heart rate
C
0.800
GeneticVariation
GWASDB
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
23583979
2013
rs4535251
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Body Height
T
0.700
GeneticVariation
GWASCAT
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
23563607
2013
rs4535251
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Height
T
0.700
GeneticVariation
GWASDB
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
23563607
2013
rs6445055
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Corneal Topography
0.700
GeneticVariation
GWASDB
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
23291589
2013
rs4894535
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Keratoconus
0.030
GeneticVariation
BEFREE
We further showed that 2 CCT-associated loci, FOXO1 and FNDC3B, conferred relatively large risks for keratoconus in 2 cohorts with 874 cases and 6,085 controls (rs2721051 near FOXO1 had odds ratio (OR) = 1.62, 95% confidence interval (CI) = 1.4-1.88, P = 2.7 × 10(-10), and rs4894535 in FNDC3B had OR = 1.47, 95% CI = 1.29-1.68, P = 4.9 × 10(-9)).
23291589
2013
rs4894535
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Keratoconus
0.030
GeneticVariation
BEFREE
The following six single-nucleotide polymorphisms (SNPs) that showed a statistically significant association with KC in a recent GWAS study were selected for genotyping in our cohort: rs4894535 (FNDC3B), rs1324183 (MPDZ-NF1B), rs1536482 (RXRA-COL5A1), rs7044529 (COL5A), rs2721051 (FOXO1), and rs9938149 (BANP-ZNF469).
24265017
2013
rs6445055
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Tonometry
A
0.700
GeneticVariation
GWASCAT
Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.
25173106
2014
rs7652177
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Body Height
C
0.700
GeneticVariation
GWASCAT
Defining the role of common variation in the genomic and biological architecture of adult human height.
25282103
2014
rs6445055
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Glaucoma, Primary Open Angle
0.010
GeneticVariation
BEFREE
We confirm genetic association of known loci for IOP and primary open-angle glaucoma (POAG ) and identify four new IOP-associated loci located on chromosome 3q25.31 within the FNDC3B gene (P = 4.19 × 10(-8) for rs6445055 ), two on chromosome 9 (P = 2.80 × 10(-11) for rs2472493 near ABCA1 and P = 6.39 × 10(-11) for rs8176693 within ABO) and one on chromosome 11p11.2 (best P = 1.04 × 10(-11) for rs747782).
25173106
2014
rs6445055
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Intraocular pressure disorder
0.010
GeneticVariation
BEFREE
We confirm genetic association of known loci for IOP and primary open-angle glaucoma (POAG) and identify four new IOP -associated loci located on chromosome 3q25.31 within the FNDC3B gene (P = 4.19 × 10(-8) for rs6445055 ), two on chromosome 9 (P = 2.80 × 10(-11) for rs2472493 near ABCA1 and P = 6.39 × 10(-11) for rs8176693 within ABO) and one on chromosome 11p11.2 (best P = 1.04 × 10(-11) for rs747782).
25173106
2014
rs4243400
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Body Height
A
0.700
GeneticVariation
GWASCAT
Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
25429064
2015
rs4894535
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Keratoconus
0.030
GeneticVariation
BEFREE
SNPs rs4954218 (Near RAB3GAP1 (5')), rs4894535 (FNDC3B), rs2956540 (LOX), rs3735520 (Near HGF (5')), rs1324183 (MPDZ-NF1B), rs1536482 (RXRA-COL5A1), rs7044529 (COL5A1), rs2721051 (Near FOXO1 (3')), rs9938149 (BANP-ZNF469) and rs6050307 (VSX1) were assessed for their association with KC .
25675348
2015
rs397778518
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Reticulocyte count (procedure)
CT
0.700
GeneticVariation
GWASCAT
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
27863252
2016
rs6763687
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
RDW - Red blood cell distribution width result
T
0.700
GeneticVariation
GWASCAT
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
27863252
2016
rs6763687
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Red cell distribution width determination
T
0.700
GeneticVariation
GWASCAT
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
27863252
2016
rs12493901
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Smoking
A
0.700
GeneticVariation
GWASCAT
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
28443625
2017
rs12493901
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Physical Activity Measurement
G
0.700
GeneticVariation
GWASCAT
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
28448500
2017
rs12493901
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Smoking Behaviors
A
0.700
GeneticVariation
GWASCAT
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
28443625
2017
rs35461662
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
Red cell distribution width determination
A
0.700
GeneticVariation
GWASCAT
Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
28957414
2017
rs35461662
×
Entrez Id:
64778
Gene Symbol:
FNDC3B
FNDC3B
RDW - Red blood cell distribution width result
A
0.700
GeneticVariation
GWASCAT
Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
28957414
2017