Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs111698934
rs111698934
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0339573
Disease:
Glaucoma, Primary Open Angle 		0.010 GeneticVariation BEFREE An association with POAG in FNDC3B (rs111698934; P < 3.9×10<sup>-5</sup>) was observed, not in linkage disequilibrium (LD) with the previously reported ED SNP. 30352225 2019
dbSNP: rs6445055
rs6445055
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0339573
Disease:
Glaucoma, Primary Open Angle 		0.010 GeneticVariation BEFREE We confirm genetic association of known loci for IOP and primary open-angle glaucoma (POAG) and identify four new IOP-associated loci located on chromosome 3q25.31 within the FNDC3B gene (P = 4.19 × 10(-8) for rs6445055), two on chromosome 9 (P = 2.80 × 10(-11) for rs2472493 near ABCA1 and P = 6.39 × 10(-11) for rs8176693 within ABO) and one on chromosome 11p11.2 (best P = 1.04 × 10(-11) for rs747782). 25173106 2014
dbSNP: rs6445055
rs6445055
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0595921
Disease:
Intraocular pressure disorder 		0.010 GeneticVariation BEFREE We confirm genetic association of known loci for IOP and primary open-angle glaucoma (POAG) and identify four new IOP-associated loci located on chromosome 3q25.31 within the FNDC3B gene (P = 4.19 × 10(-8) for rs6445055), two on chromosome 9 (P = 2.80 × 10(-11) for rs2472493 near ABCA1 and P = 6.39 × 10(-11) for rs8176693 within ABO) and one on chromosome 11p11.2 (best P = 1.04 × 10(-11) for rs747782). 25173106 2014
dbSNP: rs4894535
rs4894535
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0022578
Disease:
Keratoconus 		0.030 GeneticVariation BEFREE SNPs rs4954218 (Near RAB3GAP1 (5')), rs4894535 (FNDC3B), rs2956540 (LOX), rs3735520 (Near HGF (5')), rs1324183 (MPDZ-NF1B), rs1536482 (RXRA-COL5A1), rs7044529 (COL5A1), rs2721051 (Near FOXO1 (3')), rs9938149 (BANP-ZNF469) and rs6050307 (VSX1) were assessed for their association with KC. 25675348 2015
dbSNP: rs4894535
rs4894535
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0022578
Disease:
Keratoconus 		0.030 GeneticVariation BEFREE We further showed that 2 CCT-associated loci, FOXO1 and FNDC3B, conferred relatively large risks for keratoconus in 2 cohorts with 874 cases and 6,085 controls (rs2721051 near FOXO1 had odds ratio (OR) = 1.62, 95% confidence interval (CI) = 1.4-1.88, P = 2.7 × 10(-10), and rs4894535 in FNDC3B had OR = 1.47, 95% CI = 1.29-1.68, P = 4.9 × 10(-9)). 23291589 2013
dbSNP: rs4894535
rs4894535
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0022578
Disease:
Keratoconus 		0.030 GeneticVariation BEFREE The following six single-nucleotide polymorphisms (SNPs) that showed a statistically significant association with KC in a recent GWAS study were selected for genotyping in our cohort: rs4894535 (FNDC3B), rs1324183 (MPDZ-NF1B), rs1536482 (RXRA-COL5A1), rs7044529 (COL5A), rs2721051 (FOXO1), and rs9938149 (BANP-ZNF469). 24265017 2013
dbSNP: rs11718418
rs11718418
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs16856859
rs16856859
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C1304746
Disease:
RDW - Red blood cell distribution width result 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs16856859
rs16856859
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0427460
Disease:
Red cell distribution width determination 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs4243400
rs4243400
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs4894539
rs4894539
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Characterizing rare and low-frequency height-associated variants in the Japanese population. 31562340 2019
dbSNP: rs4894797
rs4894797
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs4894797
rs4894797
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Characterizing rare and low-frequency height-associated variants in the Japanese population. 31562340 2019
dbSNP: rs4894803
rs4894803
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0205682
Disease:
Waist-Hip Ratio 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs7652177
rs7652177
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs7652177
rs7652177
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs9647379
rs9647379
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0205682
Disease:
Waist-Hip Ratio 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs12492846
rs12492846
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0040420
Disease:
Tonometry 		C 0.700 GeneticVariation GWASCAT Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma. 29785010 2018
dbSNP: rs12492846
rs12492846
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0040420
Disease:
Tonometry 		0.700 GeneticVariation GWASCAT Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. 30054594 2018
dbSNP: rs12897
rs12897
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C1956346
Disease:
Coronary Artery Disease 		A 0.700 GeneticVariation GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
dbSNP: rs16856911
rs16856911
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0040420
Disease:
Tonometry 		0.700 GeneticVariation GWASCAT Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. 30054594 2018
dbSNP: rs4380442
rs4380442
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0040420
Disease:
Tonometry 		G 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new loci influencing intraocular pressure. 29617998 2018
dbSNP: rs62283814
rs62283814
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0040420
Disease:
Tonometry 		C 0.700 GeneticVariation GWASCAT Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma. 29785010 2018
dbSNP: rs6445046
rs6445046
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C1720164
Disease:
Central corneal thickness 		T 0.700 GeneticVariation GWASCAT Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. 29760442 2018
dbSNP: rs7635832
rs7635832
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B
CUI: C0040420
Disease:
Tonometry 		T 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new loci influencing intraocular pressure. 29617998 2018