Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11635252
rs11635252
Entrez Id: 64784
Gene Symbol: CRTC3
CRTC3
CUI: C0948089
Disease:
Acute Coronary Syndrome
0.010 GeneticVariation BEFREE Significant decrease was identified in the total cholesterol (TC), triglyceride (TG), and weight in those with CC phenotype compared with those with CT phenotype among the cases with rs11635252 (P < .05).CRTC3 polymorphism was associated with the onset of acute coronary syndrome in Han Chinese patients, which may be related to the imbalance of the lipid metabolism. 29979427 2018
dbSNP: rs3862434
rs3862434
Entrez Id: 64784
Gene Symbol: CRTC3
CRTC3
CUI: C1862382
Disease:
SVEINSSON CHORIORETINAL ATROPHY
0.010 GeneticVariation BEFREE Statistical increase was noticed in the high density lipoprotein cholesterol (HDL-C) in those with AG phenotype compared with those with AA phenotype in those with rs3862434. 29979427 2018
dbSNP: rs11635252
rs11635252
Entrez Id: 64784
Gene Symbol: CRTC3
CRTC3
CUI: C0020557
Disease:
Hypertriglyceridemia
0.010 GeneticVariation BEFREE In conclusion, the CRTC3 polymorphism rs3862434 was associated with the plasma level of total cholesterol, and rs11635252 was associated with the risks of overweight and hypertriglyceridemia in a Chinese Han population, which might strengthen our understanding of the complex heredity of metabolic disorders. 24264430 2014
dbSNP: rs11635252
rs11635252
Entrez Id: 64784
Gene Symbol: CRTC3
CRTC3
CUI: C0025517
Disease:
Metabolic Diseases
0.010 GeneticVariation BEFREE In conclusion, the CRTC3 polymorphism rs3862434 was associated with the plasma level of total cholesterol, and rs11635252 was associated with the risks of overweight and hypertriglyceridemia in a Chinese Han population, which might strengthen our understanding of the complex heredity of metabolic disorders. 24264430 2014
dbSNP: rs3862434
rs3862434
Entrez Id: 64784
Gene Symbol: CRTC3
CRTC3
CUI: C0020557
Disease:
Hypertriglyceridemia
0.010 GeneticVariation BEFREE In conclusion, the CRTC3 polymorphism rs3862434 was associated with the plasma level of total cholesterol, and rs11635252 was associated with the risks of overweight and hypertriglyceridemia in a Chinese Han population, which might strengthen our understanding of the complex heredity of metabolic disorders. 24264430 2014
dbSNP: rs3862434
rs3862434
Entrez Id: 64784
Gene Symbol: CRTC3
CRTC3
CUI: C0025517
Disease:
Metabolic Diseases
0.010 GeneticVariation BEFREE In conclusion, the CRTC3 polymorphism rs3862434 was associated with the plasma level of total cholesterol, and rs11635252 was associated with the risks of overweight and hypertriglyceridemia in a Chinese Han population, which might strengthen our understanding of the complex heredity of metabolic disorders. 24264430 2014