DisGeNET - a database of gene-disease associations

CRTC3, CREB regulated transcription coactivator 3, 64784

N. diseases: 27; N. variants: 6

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C0021390
Disease:

Inflammatory Bowel Diseases

0.800

GeneticVariation

GWASCAT

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

28067908

2017

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C0021390
Disease:

Inflammatory Bowel Diseases

0.800

GeneticVariation

GWASDB

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

23128233

2012

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C0021390
Disease:

Inflammatory Bowel Diseases

0.800

GeneticVariation

GWASCAT

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

23128233

2012

dbSNP:

rs145778816

Entrez Id:	64784
Gene Symbol:	CRTC3

CRTC3

CUI:	C0871470
Disease:

Systolic Pressure

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C3554460
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 12

0.700

GeneticVariation

GWASCAT

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

31089142

2019

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C0346629
Disease:

Malignant neoplasm of large intestine

0.700

GeneticVariation

GWASCAT

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

31089142

2019

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C2677123
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 3

0.700

GeneticVariation

GWASCAT

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

31089142

2019

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

GWASCAT

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

31089142

2019

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C1837315
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 1

0.700

GeneticVariation

GWASCAT

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

31089142

2019

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C0007102
Disease:

Malignant tumor of colon

0.700

GeneticVariation

GWASCAT

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

31089142

2019

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C0009402
Disease:

Colorectal Carcinoma

0.700

GeneticVariation

GWASCAT

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

31089142

2019

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C2675481
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 10

0.700

GeneticVariation

GWASCAT

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

31089142

2019

dbSNP:

rs7495132

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C1319315
Disease:

Adenocarcinoma of large intestine

0.700

GeneticVariation

GWASCAT

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

31089142

2019

dbSNP:

rs16944613

Entrez Id:	64784;112268163
Gene Symbol:	CRTC3;LOC112268163

CRTC3;LOC112268163

CUI:	C1319315
Disease:

Adenocarcinoma of large intestine

0.700

GeneticVariation

GWASCAT

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

29228715

2017

dbSNP:

rs16944613

Entrez Id:	64784;112268163
Gene Symbol:	CRTC3;LOC112268163

CRTC3;LOC112268163

CUI:	C1837315
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 1

0.700

GeneticVariation

GWASCAT

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

29228715

2017

dbSNP:

rs16944613

Entrez Id:	64784;112268163
Gene Symbol:	CRTC3;LOC112268163

CRTC3;LOC112268163

CUI:	C2675481
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 10

0.700

GeneticVariation

GWASCAT

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

29228715

2017

dbSNP:

rs16944613

Entrez Id:	64784;112268163
Gene Symbol:	CRTC3;LOC112268163

CRTC3;LOC112268163

CUI:	C2677123
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 3

0.700

GeneticVariation

GWASCAT

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

29228715

2017

dbSNP:

rs16944613

Entrez Id:	64784;112268163
Gene Symbol:	CRTC3;LOC112268163

CRTC3;LOC112268163

CUI:	C3554460
Disease:

COLORECTAL CANCER, SUSCEPTIBILITY TO, 12

0.700

GeneticVariation

GWASCAT

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

29228715

2017

dbSNP:

rs16944613

Entrez Id:	64784;112268163
Gene Symbol:	CRTC3;LOC112268163

CRTC3;LOC112268163

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

GWASCAT

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

29228715

2017

dbSNP:

rs16944613

Entrez Id:	64784;112268163
Gene Symbol:	CRTC3;LOC112268163

CRTC3;LOC112268163

CUI:	C0009402
Disease:

Colorectal Carcinoma

0.700

GeneticVariation

GWASCAT

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

29228715

2017

dbSNP:

rs16944613

Entrez Id:	64784;112268163
Gene Symbol:	CRTC3;LOC112268163

CRTC3;LOC112268163

CUI:	C0007102
Disease:

Malignant tumor of colon

0.700

GeneticVariation

GWASCAT

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

29228715

2017

dbSNP:

rs16944613

Entrez Id:	64784;112268163
Gene Symbol:	CRTC3;LOC112268163

CRTC3;LOC112268163

CUI:	C0346629
Disease:

Malignant neoplasm of large intestine

0.700

GeneticVariation

GWASCAT

Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

29228715

2017

dbSNP:

rs7165170

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C0021390
Disease:

Inflammatory Bowel Diseases

0.700

GeneticVariation

GWASCAT

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

26192919

2015

dbSNP:

rs7165170

Entrez Id:	64784;101926895
Gene Symbol:	CRTC3;CRTC3-AS1

CRTC3;CRTC3-AS1

CUI:	C0010346
Disease:

Crohn Disease

0.700

GeneticVariation

GWASCAT

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

26192919

2015

dbSNP:

rs11635252

Entrez Id:	64784
Gene Symbol:	CRTC3

CRTC3

CUI:	C0206698
Disease:

Cholangiocarcinoma

0.010

GeneticVariation

BEFREE

Significant decrease was identified in the total cholesterol (TC), triglyceride (TG), and weight in those with CC phenotype compared with those with CT phenotype among the cases with rs11635252 (P < .05).CRTC3 polymorphism was associated with the onset of acute coronary syndrome in Han Chinese patients, which may be related to the imbalance of the lipid metabolism.

29979427

2018