|
rs17674580
|
SLC14A1;LOC105372093
|
Malignant neoplasm of urinary bladder
|
|
0.730 |
GeneticVariation |
BEFREE |
Genome-wide association studies have confirmed association of TP63C/T rs710521, TERTC/T rs2736098, and SLC14A1C/T rs17674580 gene variants with susceptibility to bladder cancer (BC) in European and White population.
|
25218484 |
2014 |
|
rs17674580
|
SLC14A1;LOC105372093
|
Carcinoma of bladder
|
|
0.730 |
GeneticVariation |
BEFREE |
Genome-wide association studies have confirmed association of TP63C/T rs710521, TERTC/T rs2736098, and SLC14A1C/T rs17674580 gene variants with susceptibility to bladder cancer (BC) in European and White population.
|
25218484 |
2014 |
|
rs17674580
|
SLC14A1;LOC105372093
|
Carcinoma of bladder
|
|
0.730 |
GeneticVariation |
BEFREE |
Overall, seven of the 14 variants were significantly associated with bladder cancer risk (p = 9.763 × 10(-3) for rs9642880 at 8q24.21, p = 3.004 × 10(-3) for rs2294008 at 8q24.3, p = 0.012 for rs798766 at 4p16.3, p = 0.034 for rs1495741 at 8p22, p = 2.306 × 10(-4) for GSTM1, p = 8.507 × 10(-8) for rs17674580 at 18q12.3, p = 7.179 × 10(-4) for rs10936599 at 3q26.2) and the odds ratios (ORs) ranged from 1.13 to 1.65.
|
24740636 |
2014 |
|
rs17674580
|
SLC14A1;LOC105372093
|
Malignant neoplasm of urinary bladder
|
|
0.730 |
GeneticVariation |
BEFREE |
Overall, seven of the 14 variants were significantly associated with bladder cancer risk (p = 9.763 × 10(-3) for rs9642880 at 8q24.21, p = 3.004 × 10(-3) for rs2294008 at 8q24.3, p = 0.012 for rs798766 at 4p16.3, p = 0.034 for rs1495741 at 8p22, p = 2.306 × 10(-4) for GSTM1, p = 8.507 × 10(-8) for rs17674580 at 18q12.3, p = 7.179 × 10(-4) for rs10936599 at 3q26.2) and the odds ratios (ORs) ranged from 1.13 to 1.65.
|
24740636 |
2014 |
|
rs17674580
|
SLC14A1;LOC105372093
|
Malignant neoplasm of urinary bladder
|
|
0.730 |
GeneticVariation |
BEFREE |
It is speculated that rs17674580, or other sequence variants in LD with it, indirectly modifies UBC risk by affecting urine production.
|
21750109 |
2011 |
|
rs17674580
|
SLC14A1;LOC105372093
|
Carcinoma of bladder
|
|
0.730 |
GeneticVariation |
BEFREE |
It is speculated that rs17674580, or other sequence variants in LD with it, indirectly modifies UBC risk by affecting urine production.
|
21750109 |
2011 |
|
rs10775480
|
SLC14A1;LOC105372093
|
Carcinoma of bladder
|
|
0.710 |
GeneticVariation |
BEFREE |
Our data suggest that SLC14A1 could be a unique urea transporter in the bladder that has the ability to influence urine concentration and that this mechanism might explain the increased bladder cancer susceptibility associated with rs10775480.
|
23754249 |
2013 |
|
rs10775480
|
SLC14A1;LOC105372093
|
Malignant neoplasm of urinary bladder
|
|
0.710 |
GeneticVariation |
BEFREE |
Our data suggest that SLC14A1 could be a unique urea transporter in the bladder that has the ability to influence urine concentration and that this mechanism might explain the increased bladder cancer susceptibility associated with rs10775480.
|
23754249 |
2013 |
|
rs17674580
|
SLC14A1;LOC105372093
|
Bladder Neoplasm
|
|
0.020 |
GeneticVariation |
BEFREE |
Genome-wide association studies have confirmed association of TP63C/T rs710521, TERTC/T rs2736098, and SLC14A1C/T rs17674580 gene variants with susceptibility to bladder cancer (BC) in European and White population.
|
25218484 |
2014 |
|
rs17674580
|
SLC14A1;LOC105372093
|
Bladder Neoplasm
|
|
0.020 |
GeneticVariation |
BEFREE |
Overall, seven of the 14 variants were significantly associated with bladder cancer risk (p = 9.763 × 10(-3) for rs9642880 at 8q24.21, p = 3.004 × 10(-3) for rs2294008 at 8q24.3, p = 0.012 for rs798766 at 4p16.3, p = 0.034 for rs1495741 at 8p22, p = 2.306 × 10(-4) for GSTM1, p = 8.507 × 10(-8) for rs17674580 at 18q12.3, p = 7.179 × 10(-4) for rs10936599 at 3q26.2) and the odds ratios (ORs) ranged from 1.13 to 1.65.
|
24740636 |
2014 |
|
rs10775480
|
SLC14A1;LOC105372093
|
Bladder Neoplasm
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data suggest that SLC14A1 could be a unique urea transporter in the bladder that has the ability to influence urine concentration and that this mechanism might explain the increased bladder cancer susceptibility associated with rs10775480.
|
23754249 |
2013 |