SOD2, superoxide dismutase 2, 6648

N. diseases: 668; N. variants: 32
Disease: Bladder Neoplasm ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs953038635
rs953038635
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C0005695
Disease:
Bladder Neoplasm 		0.020 GeneticVariation BEFREE This systematic review and meta-analysis demonstrated that the GPX1 Pro198Leu polymorphism significantly increased susceptibility to bladder cancer, while the MnSOD Ala-9Val polymorphism was not associated with bladder cancer risk. 24037914 2014
dbSNP: rs953038635
rs953038635
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C0005695
Disease:
Bladder Neoplasm 		0.020 GeneticVariation BEFREE The GPX1 Pro/Leu genotype may significantly increase the risk of bladder cancer and the increased risk may be modified by the Ala-9Val MnSOD polymorphism. 15247771 2004
dbSNP: rs1141718
rs1141718
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C0005695
Disease:
Bladder Neoplasm 		0.010 GeneticVariation BEFREE The detoxifying enzymes inactivate dangerous chemical compounds and anions for the cell; that is, why it is important to know if the polymorphisms pro198leu in GPX-1 and ile58thr in MnSOD are associated with bladder cancer. 20441054 2010