SST, somatostatin, 6750

N. diseases: 535; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4988514
rs4988514
Entrez Id: 6750
Gene Symbol: SST
SST
CUI: C0002395
Disease:
Alzheimer's Disease 		0.020 GeneticVariation BEFREE Our results supported the notion that the C allele of the rs4988514 polymorphism may increase the risk for AD in the Chinese population and possibly have additive effect with the APOE epsilon4 allele. 19733630 2009
dbSNP: rs4988514
rs4988514
Entrez Id: 6750
Gene Symbol: SST
SST
CUI: C0002395
Disease:
Alzheimer's Disease 		0.020 GeneticVariation BEFREE Additionally, SNP rs4988514 may interact with the APOE epsilon4-allele to increase the risk of AD. 17987251 2007
dbSNP: rs3755792
rs3755792
Entrez Id: 6750
Gene Symbol: SST
SST
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE In drinking population, rs3755792 at SST was associated with hypertension incidence, and the adjusted HR was 0.580 (P = .009). 29426577 2018
dbSNP: rs7624906
rs7624906
Entrez Id: 6750
Gene Symbol: SST
SST
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE The follow-up study indicated that in smoking population, variants at SST presented significant association with hypertension incidence; the adjusted HR of rs3755792 (GA + AA vs. GG) was 0.634 (P = .037), and the adjusted HR of rs7624906 (TC + CC vs. TT) was 1.803 (P = .005). 29426577 2018
dbSNP: rs34872250
rs34872250
Entrez Id: 6750
Gene Symbol: SST
SST
CUI: C0028754
Disease:
Obesity 		0.010 GeneticVariation BEFREE The aim of this study was to evaluate the association between a poly-T repeat sequence (rs34872250) in the promoter of the SST gene and blood pressure, according to the obesity status. 26818653 2016