SSTR5, somatostatin receptor 5, 6755

N. diseases: 75; N. variants: 7
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4988483
rs4988483
Entrez Id: 6755;146336
Gene Symbol: SSTR5;SSTR5-AS1
SSTR5;SSTR5-AS1
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.010 GeneticVariation BEFREE Our results suggest that genetic variation in the SSTR5 gene and, particularly, the rs4988483 single nucleotide polymorphism influence circulating IGFI and IGFBP3 hormone levels with no measurable effect on prostate cancer risk. 19423539 2009
dbSNP: rs4988483
rs4988483
Entrez Id: 6755;146336
Gene Symbol: SSTR5;SSTR5-AS1
SSTR5;SSTR5-AS1
CUI: C1970945
Disease:
MAJOR AFFECTIVE DISORDER 6 		0.010 GeneticVariation BEFREE For the British population we found association to BPAD with missense mutation Leu48Met</span> (P = 0.003) and missense mutation Pro335Leu (P = 0.004). 12192619 2002
dbSNP: rs4988483
rs4988483
Entrez Id: 6755;146336
Gene Symbol: SSTR5;SSTR5-AS1
SSTR5;SSTR5-AS1
CUI: C0235974
Disease:
Pancreatic carcinoma 		0.010 GeneticVariation BEFREE Furthermore, the SSTR5 L48M AC variant and smoking had a joint effect on pancreatic cancer risk (p(interaction) = 0.035). 21692047 2011
dbSNP: rs4988483
rs4988483
Entrez Id: 6755;146336
Gene Symbol: SSTR5;SSTR5-AS1
SSTR5;SSTR5-AS1
CUI: C0346647
Disease:
Malignant neoplasm of pancreas 		0.010 GeneticVariation BEFREE Furthermore, the SSTR5 L48M AC variant and smoking had a joint effect on pancreatic cancer risk (p(interaction) = 0.035). 21692047 2011
dbSNP: rs4988483
rs4988483
Entrez Id: 6755;146336
Gene Symbol: SSTR5;SSTR5-AS1
SSTR5;SSTR5-AS1
CUI: C1970943
Disease:
MAJOR AFFECTIVE DISORDER 4 		0.010 GeneticVariation BEFREE For the British population we found association to BPAD with missense mutation Leu48Met</span> (P = 0.003) and missense mutation Pro335Leu (P = 0.004). 12192619 2002
dbSNP: rs4988483
rs4988483
Entrez Id: 6755;146336
Gene Symbol: SSTR5;SSTR5-AS1
SSTR5;SSTR5-AS1
CUI: C1839839
Disease:
MAJOR AFFECTIVE DISORDER 2 		0.010 GeneticVariation BEFREE For the British population we found association to BPAD with missense mutation Leu48Met</span> (P = 0.003) and missense mutation Pro335Leu (P = 0.004). 12192619 2002
dbSNP: rs4988487
rs4988487
Entrez Id: 6755;146336
Gene Symbol: SSTR5;SSTR5-AS1
SSTR5;SSTR5-AS1
CUI: C0235974
Disease:
Pancreatic carcinoma 		0.010 GeneticVariation BEFREE The SSTR5 P109S variant allele was associated with a 1.62-fold increased risk of pancreatic cancer (95% confidence interval [CI]: 1.08-2.43, P = 0.019). 21692047 2011
dbSNP: rs4988487
rs4988487
Entrez Id: 6755;146336
Gene Symbol: SSTR5;SSTR5-AS1
SSTR5;SSTR5-AS1
CUI: C0346647
Disease:
Malignant neoplasm of pancreas 		0.010 GeneticVariation BEFREE The SSTR5 P109S variant allele was associated with a 1.62-fold increased risk of pancreatic cancer (95% confidence interval [CI]: 1.08-2.43, P = 0.019). 21692047 2011
dbSNP: rs642249
rs642249
Entrez Id: 6755;146336
Gene Symbol: SSTR5;SSTR5-AS1
SSTR5;SSTR5-AS1
CUI: C0001206
Disease:
Acromegaly 		0.010 GeneticVariation BEFREE Three SNPs (rs34037914, rs169068, and rs642249) were significantly associated with the presence of acromegaly using the initial controls. 21810856 2011