rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
T
0.900
GeneticVariation
GWASDB
GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.
24871463
2014
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
T
0.900
GeneticVariation
GWASDB
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
23273568
2013
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Liver carcinoma
G
0.900
GeneticVariation
GWASDB
The risk allele G at rs7574865 was significantly associated with lower mRNA levels of STAT4 in both the HCC tissues and nontumor tissues of 155 individuals with HBV-related HCC (P(trend ) = 0.0008 and 0.0002, respectively).
23242368
2013
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Rheumatoid Arthritis
0.900
GeneticVariation
GWASDB
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.
22446963
2012
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
T
0.900
GeneticVariation
GWASDB
Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis.
23053960
2012
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Rheumatoid Arthritis
0.900
GeneticVariation
GWASDB
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
23143596
2012
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Autoimmune Diseases
T
0.900
GeneticVariation
GWASDB
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
21383967
2011
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
T
0.900
GeneticVariation
GWASDB
For example, rs7574865 in STAT4 had an OR for anti-dsDNA + SLE of 1.77 (95% CI 1.57-1.99, p = 2.0E-20) compared to an OR for anti-dsDNA - SLE of 1.26 (95% CI 1.12-1.41, p = 2.4E-04), with p(heterogeneity)<0.0005.
21408207
2011
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Rheumatoid Arthritis
T
0.900
GeneticVariation
GWASDB
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
20453842
2010
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
A
0.900
GeneticVariation
GWASDB
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.
19838193
2009
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
0.900
GeneticVariation
GWASDB
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
18204446
2008
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
T
0.900
GeneticVariation
GWASDB
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
18204098
2008
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Systemic Scleroderma
T
0.870
GeneticVariation
GWASDB
Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis.
21750679
2011
rs10181656
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Rheumatoid Arthritis
0.820
GeneticVariation
GWASDB
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
23143596
2012
rs7574070
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Behcet Syndrome
A
0.810
GeneticVariation
GWASDB
Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.
23291587
2013
rs7601754
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
0.810
GeneticVariation
GWASDB
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
23273568
2013
rs7574070
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Behcet Syndrome
0.810
GeneticVariation
GWASDB
Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.
23001997
2012
rs7574865
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Primary biliary cirrhosis
T
0.810
GeneticVariation
GWASDB
Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.
23000144
2012
rs3821236
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
0.810
GeneticVariation
GWASDB
Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
21408207
2011
rs3821236
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Lupus Erythematosus, Systemic
0.810
GeneticVariation
GWASDB
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.
19165918
2008
rs11889341
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Rheumatoid Arthritis
T
0.800
GeneticVariation
GWASDB
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
24390342
2014
rs10168266
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Sjogren's Syndrome
T
0.800
GeneticVariation
GWASDB
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23.
24097066
2013
rs10174238
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Oligoarticular Juvenile Idiopathic Arthritis
0.800
GeneticVariation
GWASDB
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
23603761
2013
rs7601754
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Systemic Scleroderma
0.800
GeneticVariation
GWASDB
A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.
23740937
2013
rs13426947
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Rheumatoid Arthritis
0.800
GeneticVariation
GWASDB
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
23143596
2012