AURKA, aurora kinase A, 6790

N. diseases: 245; N. variants: 15
Disease: Malignant neoplasm of prostate ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2273535
rs2273535
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.020 GeneticVariation BEFREE Therefore, we investigated in this Caucasian case-control study two single nucleotide polymorphisms (SNPs) of the AURKA gene, rs8173 located in the 3'-untranslated region (G1891C) and rs2273535 in exon 5 (Phe31Ile), and their association with prostate cancer risk. 18802780 2009
dbSNP: rs2273535
rs2273535
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.020 GeneticVariation BEFREE The single-nucleotide polymorphism T91A (Phe31Ile) has been implicated in AURKA overexpression and has been suggested as a low-penetrance susceptibility allele in multiple human cancers, including prostate cancer. 17898866 2007
dbSNP: rs8173
rs8173
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.010 GeneticVariation BEFREE Therefore, we investigated in this Caucasian case-control study two single nucleotide polymorphisms (SNPs) of the AURKA gene, rs8173 located in the 3'-untranslated region (G1891C) and rs2273535 in exon 5 (Phe31Ile), and their association with prostate cancer risk. 18802780 2009