|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Breast Carcinoma
|
|
0.030 |
GeneticVariation |
BEFREE |
All in all, our meta-analysis had successfully chased down that miR-618 rs2682818</span> polymorphism is not linked with overall cancer risk, but in the dominant genotype of breast cancer.
|
31383788 |
2019 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Malignant neoplasm of breast
|
|
0.030 |
GeneticVariation |
BEFREE |
All in all, our meta-analysis had successfully chased down that miR-618 rs2682818</span> polymorphism is not linked with overall cancer risk, but in the dominant genotype of breast cancer.
|
31383788 |
2019 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Breast Carcinoma
|
|
0.030 |
GeneticVariation |
BEFREE |
Our findings support the following conclusions: a) rs6505162:C > A in pre-miR-423 increases risk of familial BC in families with a strong history of BC; b) the C/A genotype at rs2682818:C > A (pre-miR-618) increases BC risk in non-familial early-onset BC; and c) the G/G genotype at rs895819:A > G (miR-27a) reduces BC risk in families with a moderate history of BC.
|
27421647 |
2016 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Malignant neoplasm of breast
|
|
0.030 |
GeneticVariation |
BEFREE |
Our findings support the following conclusions: a) rs6505162:C > A in pre-miR-423 increases risk of familial BC in families with a strong history of BC; b) the C/A genotype at rs2682818:C > A (pre-miR-618) increases BC risk in non-familial early-onset BC; and c) the G/G genotype at rs895819:A > G (miR-27a) reduces BC risk in families with a moderate history of BC.
|
27421647 |
2016 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Breast Carcinoma
|
|
0.030 |
GeneticVariation |
BEFREE |
To explore the relevance of miRNA polymorphisms and female physiological characteristics to breast cancer risk, SNPs located within hsa-miR-605 (rs2043556), hsa-miR-149 (rs2292832), hsa-miR-27a (rs895819), hsa-miR-196a-2 (rs11614913) and hsa-miR-618 (rs2682818) were selected, and their associations with breast cancer risk were analysed.
|
22074121 |
2012 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Malignant neoplasm of breast
|
|
0.030 |
GeneticVariation |
BEFREE |
To explore the relevance of miRNA polymorphisms and female physiological characteristics to breast cancer risk, SNPs located within hsa-miR-605 (rs2043556), hsa-miR-149 (rs2292832), hsa-miR-27a (rs895819), hsa-miR-196a-2 (rs11614913) and hsa-miR-618 (rs2682818) were selected, and their associations with breast cancer risk were analysed.
|
22074121 |
2012 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation |
BEFREE |
All in all, our meta-analysis had successfully chased down that miR-618 rs2682818 polymorphism is not linked with overall cancer risk, but in the dominant genotype of breast cancer.
|
31383788 |
2019 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Carcinogenesis
|
|
0.010 |
GeneticVariation |
BEFREE |
Piles of evidence have supported the relationship between miR-618 rs2682818 polymorphism and tumorigenesis, but the conclusion remains inconsistent.
|
31383788 |
2019 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Malignant tumor of cervix
|
|
0.010 |
GeneticVariation |
BEFREE |
Because genetic variants in microRNAs (miRNAs) or their surrounding regions can alter miRNA processing, expression and final biological function, we investigated whether miRNA single-nucleotide polymorphisms (SNPs) are associated with cervical cancer (CC) susceptibility.Common miRNA SNPs (i.e. miR-146a rs2910164, miR-149 rs2292832, miR-196a2 rs11614913, miR-499 rs3746444, miR-605 rs2043556 and miR-618 rs2682818) were genotyped in the 954 patients and 1339 controls.
|
30852614 |
2019 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
cervical cancer
|
|
0.010 |
GeneticVariation |
BEFREE |
Because genetic variants in microRNAs (miRNAs) or their surrounding regions can alter miRNA processing, expression and final biological function, we investigated whether miRNA single-nucleotide polymorphisms (SNPs) are associated with cervical cancer (CC) susceptibility.Common miRNA SNPs (i.e. miR-146a rs2910164, miR-149 rs2292832, miR-196a2 rs11614913, miR-499 rs3746444, miR-605 rs2043556 and miR-618 rs2682818) were genotyped in the 954 patients and 1339 controls.
|
30852614 |
2019 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation |
BEFREE |
All in all, our meta-analysis had successfully chased down that miR-618 rs2682818 polymorphism is not linked with overall cancer risk, but in the dominant genotype of breast cancer.
|
31383788 |
2019 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Cervix carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
Because genetic variants in microRNAs (miRNAs) or their surrounding regions can alter miRNA processing, expression and final biological function, we investigated whether miRNA single-nucleotide polymorphisms (SNPs) are associated with cervical cancer (CC) susceptibility.Common miRNA SNPs (i.e. miR-146a rs2910164, miR-149 rs2292832, miR-196a2 rs11614913, miR-499 rs3746444, miR-605 rs2043556 and miR-618 rs2682818) were genotyped in the 954 patients and 1339 controls.
|
30852614 |
2019 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
SNP rs2682818 in miR-618 has potential as a biomarker for individuals with high CRC susceptibility.
|
29533012 |
2018 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Malignant neoplasm of colon and/or rectum
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphism rs2682818 in miR-618 is associated with colorectal cancer susceptibility in a Han Chinese population.
|
29533012 |
2018 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Ischemic stroke
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, the variant genotypes (GT/TT) </span>of rs26</span>82818 were an independent prognostic factor for ischemic stroke in the multivariate Cox regression model.
|
27011381 |
2017 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Familial (FPAH)
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study evaluated the association of the SNPs rs895819 in pre-miR27a, rs11614913 in pre-miR-196a2, rs6505162 in pre-miR-423, rs4919510 in miR-608, and rs2682818 in pre-mir-618 with familial BC and early-onset non-familial BC in non-carriers of BRCA1/2 mutations from a South American population.
|
27421647 |
2016 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Lymphoma, Non-Hodgkin
|
|
0.010 |
GeneticVariation |
BEFREE |
Findings were confirmed by genotyping a SNP (rs2682818) in the stem-loop sequence of miR-618 in a population-based case-control study of NHL (455 cases and 527 controls).
|
24503492 |
2014 |
|
rs2682818
|
LIN7A;MIR618;LOC105369869
|
Lymphoma, Follicular
|
|
0.010 |
GeneticVariation |
BEFREE |
This is consistent with our finding of a significant association between rs2682818 G>T in the miR-618 stem-loop and follicular lymphoma (FL) (OR: 1.65, 95% CI: 1.05-2.60).
|
24503492 |
2014 |