DisGeNET - a database of gene-disease associations

TECTA, tectorin alpha, 7007

N. diseases: 24; N. variants: 28

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs140236996

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

CausalMutation

CLINVAR

TECTA mutations in Japanese with mid-frequency hearing loss affected by zona pellucida domain protein secretion.

22718023

2012

dbSNP:

rs140236996

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

CausalMutation

CLINVAR

DFNA8/12 caused by TECTA mutations is the most identified subtype of nonsyndromic autosomal dominant hearing loss.

21520338

2011

dbSNP:

rs140236996

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

CausalMutation

CLINVAR

Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in Middle Eastern families.

21917145

2011

dbSNP:

rs140236996

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

CausalMutation

CLINVAR

Two novel missense mutations in the TECTA gene in Korean families with autosomal dominant nonsyndromic hearing loss.

20947814

2010

dbSNP:

rs121909058

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

Distinctive audiometric profile associated with DFNB21 alleles of TECTA.

12746400

2003

dbSNP:

rs121909059

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

Distinctive audiometric profile associated with DFNB21 alleles of TECTA.

12746400

2003

dbSNP:

rs121909060

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

Distinctive audiometric profile associated with DFNB21 alleles of TECTA.

12746400

2003

dbSNP:

rs121909061

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

Distinctive audiometric profile associated with DFNB21 alleles of TECTA.

12746400

2003

dbSNP:

rs121909063

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

Distinctive audiometric profile associated with DFNB21 alleles of TECTA.

12746400

2003

dbSNP:

rs140236996

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

Distinctive audiometric profile associated with DFNB21 alleles of TECTA.

12746400

2003

dbSNP:

rs121909058

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB21.

9949200

1999

dbSNP:

rs121909059

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB21.

9949200

1999

dbSNP:

rs121909060

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB21.

9949200

1999

dbSNP:

rs121909061

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB21.

9949200

1999

dbSNP:

rs121909063

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB21.

9949200

1999

dbSNP:

rs140236996

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

GeneticVariation

UNIPROT

An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB21.

9949200

1999

dbSNP:

rs121909058

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

CausalMutation

CLINVAR

dbSNP:

rs121909059

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

CausalMutation

CLINVAR

dbSNP:

rs121909060

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

CausalMutation

CLINVAR

dbSNP:

rs121909061

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

CausalMutation

CLINVAR

dbSNP:

rs121909061

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

CausalMutation

CLINVAR

dbSNP:

rs121909063

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.800

CausalMutation

CLINVAR

dbSNP:

rs121909062

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.700

GeneticVariation

UNIPROT

Distinctive audiometric profile associated with DFNB21 alleles of TECTA.

12746400

2003

dbSNP:

rs138768918

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.700

GeneticVariation

UNIPROT

Distinctive audiometric profile associated with DFNB21 alleles of TECTA.

12746400

2003

dbSNP:

rs1428598791

Entrez Id:	7007
Gene Symbol:	TECTA

TECTA

CUI:	C1832187
Disease:

Deafness, Autosomal Dominant 12

0.700

GeneticVariation

UNIPROT

Distinctive audiometric profile associated with DFNB21 alleles of TECTA.

12746400

2003