TLR1, toll like receptor 1, 7096

N. diseases: 198; N. variants: 52
Disease: IGA Glomerulonephritis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4833095
rs4833095
Entrez Id: 7096
Gene Symbol: TLR1
TLR1
CUI: C0017661
Disease:
IGA Glomerulonephritis 		0.020 GeneticVariation BEFREE Taken together, these findings suggest that the TLR1 rs4833095 polymorphism may play a role in the development and progression of IgAN. 27806314 2016
dbSNP: rs5743557
rs5743557
Entrez Id: 7096
Gene Symbol: TLR1
TLR1
CUI: C0017661
Disease:
IGA Glomerulonephritis 		0.020 GeneticVariation BEFREE However, there was no significant association between the genotype distributions of rs5743557 and clinical parameters of IgAN such as gender, 24 hour urine protein, blood pressure, and Lee's grades. 27806314 2016
dbSNP: rs4833095
rs4833095
Entrez Id: 7096
Gene Symbol: TLR1
TLR1
CUI: C0017661
Disease:
IGA Glomerulonephritis 		0.020 GeneticVariation BEFREE After Bonferroni correction, the association of the genotypes of rs4833095 and the CT haplotype with IgAN risk remained significant. 21108742 2011
dbSNP: rs5743557
rs5743557
Entrez Id: 7096
Gene Symbol: TLR1
TLR1
CUI: C0017661
Disease:
IGA Glomerulonephritis 		0.020 GeneticVariation BEFREE For rs5743557, the T/T genotype in the codominant model (vs. the C/C genotype) (OR = 1.74, 95% CI: 1.02-2.96, P = 0.041) appeared to be associated with IgAN risk. 21108742 2011