TLR2, toll like receptor 2, 7097

N. diseases: 749; N. variants: 15
Disease: Bipolar Disorder ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3804099
rs3804099
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0005586
Disease:
Bipolar Disorder 		0.020 GeneticVariation BEFREE The negative effects of childhood sexual abuse on age at onset of BD may be amplified in TLR2 rs3804099 risk genotype carriers through immune-mediated pathways. 25790282 2015
dbSNP: rs3804099
rs3804099
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0005586
Disease:
Bipolar Disorder 		0.020 GeneticVariation BEFREE We found that the TLR2 rs3804099 TT was significantly more prevalent in EO-BD than in LO-BD patients (corrected p (pc)=0.024). 24882191 2014
dbSNP: rs4696480
rs4696480
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0005586
Disease:
Bipolar Disorder 		0.010 GeneticVariation BEFREE After excluding family history of psychiatric disorders, we also found that the TLR2 rs4696480 TT genotype was significantly more prevalent in EO-BD as compared to LO-BD and controls (pc=0.002 and 0.002). 24882191 2014