|
rs1799964
|
LTA;TNF;LOC100287329
|
Hyperandrogenism
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, rs1799964 showed an association with dietary habit, clinical hyperandrogenism and AAO.
|
23975191 |
2013 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation |
BEFREE |
Among all pooled never smokers (588 cases and 816 controls), TNF rs1799964 was inversely associated with smoking-related cancer (CC vs. CT+TT aOR: 0.36, 95% CI: 0.17-0.77).
|
20112337 |
2010 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Lupus Nephritis
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we aimed to examine whether the TNF -238G/A, -308G/A, -376G/A (rs1800750), and -1031T/C (rs1799964) polymorphisms confer SLE or lupus nephritis (LN) susceptibility in a Mexican population.
|
29611038 |
2018 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Coronary heart disease
|
|
0.010 |
GeneticVariation |
BEFREE |
we will perform a case-control study to explore the CRP and TNF-α genotype distribution as well as the serum influence of rs1800947, rs1130864, rs2794521 and rs1205 (polymorphisms of the CRP gene) and rs361525, rs1800629, rs1799724, rs1800630, rs1799964 (of the TNF-α gene) in Mexican individuals who present coronary artery disease.
|
26751459 |
2016 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, this work was planned to evaluate the association of -863C/A (rs1800630) and -1031T/C (rs1799964) polymorphisms in TNF gene with plasma TNF-α levels and DN among subjects with type 2 diabetes (T2DM) in a population from North India.
|
25704106 |
2015 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to determine whether the TNF -1031T/C (rs1799964), -376G/A (rs1800750), -308G/A (rs1800629) -238G/A (rs361525), and TNFR1 -609G/T polymorphisms are associated with RA susceptibility in a sample of Mexican patients.
|
29404828 |
2018 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Cachexia
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1799964 in the TNF gene and rs4291 in the ACE gene are new associations when the definition of cachexia is based on a combination of WL and LSMI.
|
27897403 |
2017 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Malignant neoplasm of lung
|
|
0.010 |
GeneticVariation |
BEFREE |
Bayesian correction for multiple comparisons suggests that chance is unlikely to explain our findings (although epigenetic mechanisms may be in effect), which support our hypotheses, suggesting that IL10 rs1800871 is a susceptibility marker for oropharyngeal and lung cancers, and that TNF rs1799964 is associated with smoking-related cancers among never smokers.
|
20112337 |
2010 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we aimed to examine whether the TNF -238G/A, -308G/A, -376G/A (rs1800750), and -1031T/C (rs1799964) polymorphisms confer SLE or lupus nephritis (LN) susceptibility in a Mexican population.
|
29611038 |
2018 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Complicated malaria
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined a possible association of three single nucleotide polymorphisms (SNPs) of the tumor necrosis factor alpha (TNF) promoter -1031T>C (rs1799964), -863C>A (rs1800630), and -857C>T (rs1799724) with severe malaria in 466 adult patients having Plasmodium falciparum malaria in northwest Thailand.
|
17493155 |
2007 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Microcephaly
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, rs1799964 SNP at tumor necrosis factor-α gene in CZS babies is associated with severe microcephaly (OR, 2.63; 95% CI, 1.13-6.21).
|
31352487 |
2019 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Pain
|
|
0.010 |
GeneticVariation |
BEFREE |
Of the 10 SNPs evaluated in LTA and PTGS2 genes, 3 were associated with pain severity (rs5277; rs1799964), social function (rs5277) and mental health (rs5275).
|
22464751 |
2012 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Anxiety
|
|
0.010 |
GeneticVariation |
BEFREE |
Two single nucleotide polymorphisms in tumor necrosis factor-α (rs1799964, rs3093662) were associated with the higher anxiety subgroup.
|
25813148 |
2016 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Oropharyngeal disorders
|
|
0.010 |
GeneticVariation |
BEFREE |
Bayesian correction for multiple comparisons suggests that chance is unlikely to explain our findings (although epigenetic mechanisms may be in effect), which support our hypotheses, suggesting that IL10 rs1800871 is a susceptibility marker for oropharyngeal and lung cancers, and that TNF rs1799964 is associated with smoking-related cancers among never smokers.
|
20112337 |
2010 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Pouchitis
|
|
0.010 |
GeneticVariation |
BEFREE |
SNP genotyping was performed for 8 SNPs reportedly associated with UCAC and pouchitis, namely: ELF1 (rs7329174), FCGR2A, (rs1801274), interleukin-1β (IL-1B; rs1143627), ITLN1 (rs2274910), MHC (rs7765379), TNFα (rs1799964), TNFSF15 (rs3810936), and UHMK1 (rs768910), using TaqMan genotyping technologies.
|
31671425 |
2019 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Cytomegalovirus Infections
|
|
0.010 |
GeneticVariation |
BEFREE |
In multivariate analysis, the IL1B rs16944 TT and TNF rs1799964 TC genotypes were significantly associated with intrauterine CMV infection (aOR = 2.32; 95% CI, 1.11-4.89; p = 0.032, and aOR = 2.17, 95% CI, 1.25-3.77; p = 0.007, respectively).
|
28501927 |
2017 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Cardiovascular Diseases
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs (rs1800629 and rs1799964) located at the TNFA gene were genotyped by OpenArray platform in 840 subjects with established cardiovascular disease.
|
27477483 |
2016 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Chronic Periodontitis
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms of: 1) FCGR2A 131His/Arg (rs1801274); 2) FCGR2B 232Ile/Thr (rs1050501); 3) TNFA -1031T/C (rs1799964); and 4) TNFA -863C/A (rs1800630) were analyzed among patients with healthy gingiva (n = 176) and patients with CP (n = 177).
|
27063995 |
2016 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Malignant tumor of cervix
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of A allele in rs1799964 was also higher for cervi</span>cal cancer group (38.3%) than control group (16.4%; odds ratio = 1.43, 95% confidence interval = 1.07-1.91, P < .05).
|
29940817 |
2018 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Anxiety Disorders
|
|
0.010 |
GeneticVariation |
BEFREE |
Two single nucleotide polymorphisms in tumor necrosis factor-α (rs1799964, rs3093662) were associated with the higher anxiety subgroup.
|
25813148 |
2016 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, this work was planned to evaluate the association of -863C/A (rs1800630) and -1031T/C (rs1799964) polymorphisms in TNF gene with plasma TNF-α levels and DN among subjects with type 2 diabetes (T2DM) in a population from North India.
|
25704106 |
2015 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
we will perform a case-control study to explore the CRP and TNF-α genotype distribution as well as the serum influence of rs1800947, rs1130864, rs2794521 and rs1205 (polymorphisms of the CRP gene) and rs361525, rs1800629, rs1799724, rs1800630, rs1799964 (of the TNF-α gene) in Mexican individuals who present coronary artery disease.
|
26751459 |
2016 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Psoriasis
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis suggests that the coexistence of the polymorphisms rs1799964 (TNF-α), rs2010963 (VEGF), rs833061 (VEGF), and rs6311 (5HT2A) may be a protective factor for psoriasis.
|
31148856 |
2020 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Peptic Ulcer
|
|
0.010 |
GeneticVariation |
BEFREE |
TNFA-308G>A (rs1800629) and TNFA-1031T>C (rs1799964), which are responsible for increased TNFA transcription, could influence the risk of peptic ulceration.
|
25368751 |
2014 |
|
rs1799964
|
LTA;TNF;LOC100287329
|
Stomach Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
The study results revealed that IL-1β rs1143627: T > C, rs16944: C > T (p = 0.001;OR = 1.85; 95% CI 1.30-2.63) and rs1143633: G > A (p < 0.0001; OR = 2.53; 95% CI 1.67-3.83) and TNF-α rs1800630: C > A, rs1799964: T > C (p < 0.0001; OR = 2.31; 95% CI 1.54-3.46) polymorphisms significantly contributed toward GC risk.
|
30094865 |
2018 |