TMEM258, transmembrane protein 258, 746

N. diseases: 63; N. variants: 37
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0010346
Disease:
Crohn Disease 		0.810 GeneticVariation BEFREE These relate to SNPs associated with Crohn's disease (CD; rs102275) and rheumatoid arthritis (RA; rs968567), which affect the expression of miR-1908-5p (p<sub>rs102275</sub> = 1.44e-20, p<sub>rs968567</sub> = 2.54e-14). 30143393 2018
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.800 GeneticVariation GWASDB A genome-wide association study of the metabolic syndrome in Indian Asian men. 20694148 2010
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.800 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0202177
Disease:
Phospholipid measurement 		0.800 GeneticVariation GWASCAT Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. 22359512 2012
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0524620
Disease:
Metabolic Syndrome X 		0.800 GeneticVariation GWASCAT A genome-wide association study of the metabolic syndrome in Indian Asian men. 20694148 2010
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.800 GeneticVariation GWASCAT A genome-wide association study of the metabolic syndrome in Indian Asian men. 20694148 2010
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0202177
Disease:
Phospholipid measurement 		0.800 GeneticVariation GWASDB Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. 22359512 2012
dbSNP: rs1382225004
rs1382225004
Entrez Id: 745;746
Gene Symbol: MYRF;TMEM258
MYRF;TMEM258
CUI: C4748946
Disease:
CARDIAC-UROGENITAL SYNDROME 		0.800 GeneticVariation UNIPROT
dbSNP: rs174537
rs174537
Entrez Id: 745;746
Gene Symbol: MYRF;TMEM258
MYRF;TMEM258
CUI: C0202236
Disease:
Triglycerides measurement 		0.800 GeneticVariation GWASDB A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection. 19074352 2008
dbSNP: rs102274
rs102274
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0523465
Disease:
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219 2012
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0523465
Disease:
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219 2012
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0202236
Disease:
Triglycerides measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C1611184
Disease:
Calcification of coronary artery 		0.700 GeneticVariation GWASCAT Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis. 22916037 2012
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0428472
Disease:
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0428474
Disease:
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0523465
Disease:
Serum albumin measurement 		0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178 2013
dbSNP: rs102275
rs102275
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs108499
rs108499
Entrez Id: 745;746
Gene Symbol: MYRF;TMEM258
MYRF;TMEM258
CUI: C0523465
Disease:
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219 2012
dbSNP: rs108499
rs108499
Entrez Id: 745;746
Gene Symbol: MYRF;TMEM258
MYRF;TMEM258
CUI: C0202177
Disease:
Phospholipid measurement 		0.700 GeneticVariation GWASDB Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. 21829377 2011
dbSNP: rs108499
rs108499
Entrez Id: 745;746
Gene Symbol: MYRF;TMEM258
MYRF;TMEM258
CUI: C0523465
Disease:
Serum albumin measurement 		0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178 2013
dbSNP: rs149803
rs149803
Entrez Id: 745;746
Gene Symbol: MYRF;TMEM258
MYRF;TMEM258
CUI: C0523465
Disease:
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219 2012
dbSNP: rs149803
rs149803
Entrez Id: 745;746
Gene Symbol: MYRF;TMEM258
MYRF;TMEM258
CUI: C0202177
Disease:
Phospholipid measurement 		0.700 GeneticVariation GWASDB Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. 21829377 2011
dbSNP: rs149804
rs149804
Entrez Id: 745;746
Gene Symbol: MYRF;TMEM258
MYRF;TMEM258
CUI: C0523465
Disease:
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219 2012