WT1, WT1 transcription factor, 7490

N. diseases: 446; N. variants: 61
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs16754
rs16754
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0023465
Disease:
Acute monocytic leukemia
0.040 GeneticVariation BEFREE Recent works have studied the prognostic significance of WT1 polymorphisms and mutations, highlighting the role of SNP rs16754 as a positive prognostic factor in AML patients. 29407184 2018
dbSNP: rs16754
rs16754
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0023465
Disease:
Acute monocytic leukemia
0.040 GeneticVariation BEFREE The genetic variant rs16754 of Wilms tumor gene 1 (WT1) has recently been described as an independent prognostic factor in AML patients. 25932444 2015
dbSNP: rs16754
rs16754
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0023465
Disease:
Acute monocytic leukemia
0.040 GeneticVariation BEFREE We were unable to confirm the suggested favorable outcome of SNP rs16754 in de novo AML. 23070125 2012
dbSNP: rs16754
rs16754
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0023465
Disease:
Acute monocytic leukemia
0.040 GeneticVariation BEFREE To analyze the prevalence and clinical implications of Wilms' tumor 1 (WT1) single nucleotide polymorphism (SNP) rs16754 in the context of other prognostic markers in pediatric acute myeloid leukemia (AML). 21189390 2011