XRCC3, X-ray repair cross complementing 3, 7517

N. diseases: 184; N. variants: 24
Disease: Brain Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs861539
rs861539
Entrez Id: 3831;7517
Gene Symbol: KLC1;XRCC3
KLC1;XRCC3
CUI: C0006118
Disease:
Brain Neoplasms 		0.020 GeneticVariation BEFREE Subgroup analysis by race suggested that the XRCC3 Thr241Met polymorphism was associated with increased risk of brain tumors in Asians under all four contrast models (Met vs. Thr: OR = 1.22, 95 % CI 1.09-1.36, P < 0.01; MetMet vs. ThrThr: OR = 1.89, 95 % CI 1.38-2.57, P < 0.01; MetMet vs. ThrThr/ThrMet: OR = 1.78, 95 % CI 1.31-2.40, P < 0.01; and MetMet vs. ThrThr/ThrMet: OR = 1.19, 95 % CI 1.04-1.36, P = 0.01). 24061639 2014
dbSNP: rs861539
rs861539
Entrez Id: 3831;7517
Gene Symbol: KLC1;XRCC3
KLC1;XRCC3
CUI: C0006118
Disease:
Brain Neoplasms 		0.020 GeneticVariation BEFREE We evaluated the association of SNPs Arg194Trp, Arg280His, and Arg399Gln in the X-ray cross-complementing group 1 (XRCC1) and Thr241Met in the X-ray cross-complementing group 3 (XRCC3) DNA repair genes with the risk of brain tumors. 18330515 2008
dbSNP: rs745564626
rs745564626
Entrez Id: 3831;7517
Gene Symbol: KLC1;XRCC3
KLC1;XRCC3
CUI: C0006118
Disease:
Brain Neoplasms 		0.010 GeneticVariation BEFREE We evaluated the association of SNPs Arg194Trp, Arg280His, and Arg399Gln in the X-ray cross-complementing group 1 (XRCC1) and Thr241Met in the X-ray cross-complementing group 3 (XRCC3) DNA repair genes with the risk of brain tumors. 18330515 2008