IL1R2, interleukin 1 receptor type 2, 7850

N. diseases: 76; N. variants: 12
Disease: Tuberculosis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11674595
rs11674595
Entrez Id: 7850
Gene Symbol: IL1R2
IL1R2
CUI: C0041296
Disease:
Tuberculosis 		0.010 GeneticVariation BEFREE Additionally, we found three haplotypes that were associated with an increased risk of TB: TGCT and TGTT haplotypes constructed by rs11674595, rs4851527, rs719250 and rs3218896, as well as GA haplotype constructed by rs3218977 and rs2072472 (p < 0.05). 30256493 2018
dbSNP: rs4851527
rs4851527
Entrez Id: 7850
Gene Symbol: IL1R2
IL1R2
CUI: C0041296
Disease:
Tuberculosis 		0.010 GeneticVariation BEFREE In the genetic model analysis, we found that the allele 'A' of rs4851527 was correlated with a decreased risk of TB in a log-additive model, whereas the minor alleles of rs719250, rs3218977, rs10490571, rs956730 and rs3917225 were correlated with an increased risk of TB in dominant and log-additive models (p < 0.05). 30256493 2018