DisGeNET - a database of gene-disease associations

VKORC1, vitamin K epoxide reductase complex subunit 1, 79001

N. diseases: 15; N. variants: 10

Source: CURATED ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs104894539

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.800

GeneticVariation

UNIPROT

Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment.

20946155

2011

dbSNP:

rs104894540

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.800

GeneticVariation

UNIPROT

Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment.

20946155

2011

dbSNP:

rs104894541

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.800

GeneticVariation

UNIPROT

Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment.

20946155

2011

dbSNP:

rs104894539

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.800

GeneticVariation

UNIPROT

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.

14765194

2004

dbSNP:

rs104894540

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.800

GeneticVariation

UNIPROT

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.

14765194

2004

dbSNP:

rs104894541

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.800

GeneticVariation

UNIPROT

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.

14765194

2004

dbSNP:

rs104894539

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.800

CausalMutation

CLINVAR

dbSNP:

rs104894540

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.800

CausalMutation

CLINVAR

dbSNP:

rs104894541

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.800

CausalMutation

CLINVAR

dbSNP:

rs72547528

Entrez Id:	79001;339105
Gene Symbol:	VKORC1;PRSS53

VKORC1;PRSS53

CUI:	C1843832
Disease:

VITAMIN K-DEPENDENT CLOTTING FACTORS, COMBINED DEFICIENCY OF, 2

0.800

GeneticVariation

UNIPROT

dbSNP:

rs72547528

Entrez Id:	79001;339105
Gene Symbol:	VKORC1;PRSS53

VKORC1;PRSS53

CUI:	C1843832
Disease:

VITAMIN K-DEPENDENT CLOTTING FACTORS, COMBINED DEFICIENCY OF, 2

0.800

CausalMutation

CLINVAR

dbSNP:

rs61742245

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.720

GeneticVariation

UNIPROT

Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment.

20946155

2011

dbSNP:

rs61742245

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.720

GeneticVariation

UNIPROT

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.

14765194

2004

dbSNP:

rs72547529

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.720

GeneticVariation

UNIPROT

dbSNP:

rs8050894

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0424621
Disease:

Body Fat Distribution

0.700

GeneticVariation

GWASCAT

Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.

30664634

2019

dbSNP:

rs104894542

Entrez Id:	79001;339105
Gene Symbol:	VKORC1;PRSS53

VKORC1;PRSS53

CUI:	C0750384
Disease:

Coumarin Resistance

0.700

GeneticVariation

UNIPROT

Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment.

20946155

2011

dbSNP:

rs104894542

Entrez Id:	79001;339105
Gene Symbol:	VKORC1;PRSS53

VKORC1;PRSS53

CUI:	C0750384
Disease:

Coumarin Resistance

0.700

GeneticVariation

UNIPROT

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.

14765194

2004

dbSNP:

rs755767348

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.700

GeneticVariation

UNIPROT

dbSNP:

rs770703948

Entrez Id:	79001
Gene Symbol:	VKORC1

VKORC1

CUI:	C0750384
Disease:

Coumarin Resistance

0.700

GeneticVariation

UNIPROT