FBXO11, F-box protein 11, 80204

N. diseases: 93; N. variants: 619
Disease: Malignant tumor of colon ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1553413710
rs1553413710
Entrez Id: 2956;80204
Gene Symbol: MSH6;FBXO11
MSH6;FBXO11
CUI: C0007102
Disease:
Malignant tumor of colon 		T 0.700 CausalMutation CLINVAR A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry. 22949379 2013
dbSNP: rs1021631442
rs1021631442
Entrez Id: 2956;80204
Gene Symbol: MSH6;FBXO11
MSH6;FBXO11
CUI: C0007102
Disease:
Malignant tumor of colon 		A 0.700 GeneticVariation CLINVAR Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer. 23047549 2012
dbSNP: rs267608058
rs267608058
Entrez Id: 2956;80204
Gene Symbol: MSH6;FBXO11
MSH6;FBXO11
CUI: C0007102
Disease:
Malignant tumor of colon 		A 0.700 CausalMutation CLINVAR
dbSNP: rs267608078
rs267608078
Entrez Id: 2956;80204
Gene Symbol: MSH6;FBXO11
MSH6;FBXO11
CUI: C0007102
Disease:
Malignant tumor of colon 		AC 0.700 CausalMutation CLINVAR
dbSNP: rs63750767
rs63750767
Entrez Id: 2956;80204
Gene Symbol: MSH6;FBXO11
MSH6;FBXO11
CUI: C0007102
Disease:
Malignant tumor of colon 		TTCAAAAGGGACATAGAAAA 0.700 CausalMutation CLINVAR
dbSNP: rs864622607
rs864622607
Entrez Id: 2956;80204
Gene Symbol: MSH6;FBXO11
MSH6;FBXO11
CUI: C0007102
Disease:
Malignant tumor of colon 		G 0.700 GeneticVariation CLINVAR
dbSNP: rs869312770
rs869312770
Entrez Id: 2956;80204
Gene Symbol: MSH6;FBXO11
MSH6;FBXO11
CUI: C0007102
Disease:
Malignant tumor of colon 		C 0.700 CausalMutation CLINVAR
dbSNP: rs536562413
rs536562413
Entrez Id: 2956;80204
Gene Symbol: MSH6;FBXO11
MSH6;FBXO11
CUI: C0007102
Disease:
Malignant tumor of colon 		0.010 GeneticVariation BEFREE Statistically significant interactions were observed between: MLH1 -93G>A and smoking (MSI-negative colon cancer only, p value interaction: 0.005); and MLH1 Ile219Val and Western diet (p value interaction: 0.03). 18523027 2009
dbSNP: rs587780669
rs587780669
Entrez Id: 2956;80204
Gene Symbol: MSH6;FBXO11
MSH6;FBXO11
CUI: C0007102
Disease:
Malignant tumor of colon 		0.010 GeneticVariation BEFREE The MSH6 Gly39Glu and MLH1 -93G>A polymorphisms were associated with risk of overall colon and MSI-positive colon cancers, respectively. 18523027 2009