TET1, tet methylcytosine dioxygenase 1, 80312

N. diseases: 156; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10998288
rs10998288
Entrez Id: 80312
Gene Symbol: TET1
TET1
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs35787829
rs35787829
Entrez Id: 80312
Gene Symbol: TET1
TET1
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Characterizing rare and low-frequency height-associated variants in the Japanese population. 31562340 2019
dbSNP: rs2298117
rs2298117
Entrez Id: 80312
Gene Symbol: TET1
TET1
CUI: C0202236
Disease:
Triglycerides measurement 		T 0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs3814177
rs3814177
Entrez Id: 80312
Gene Symbol: TET1
TET1
CUI: C0027651
Disease:
Neoplasms 		0.010 GeneticVariation BEFREE In addition, there was suggestive evidence of association for ten-eleven translocation (TET) genes variance with tumour response (TET1 rs3814177, odds ratio [OR] = 0.76, 95% CI 0.59-0.97, P = 0.025, FDR = 0.087; TET3 rs7560668, OR = 1.44; 95% CI 1.10-1.89; P = 0.009; FDR = 0.062). 30852420 2019
dbSNP: rs150689919
rs150689919
Entrez Id: 80312
Gene Symbol: TET1
TET1
CUI: C0030567
Disease:
Parkinson Disease 		0.010 GeneticVariation BEFREE Our findings suggest that rs150689919 in TET1 may not be associated with PD in Chinese population. 24325350 2013
dbSNP: rs5030882
rs5030882
Entrez Id: 80312
Gene Symbol: TET1
TET1
CUI: C0494463
Disease:
Alzheimer Disease, Late Onset 		0.010 GeneticVariation BEFREE We demonstrated nominally significant association with LOAD for 4 SNPs: rs1881747 near DKK1 (P = 0.011, OR = 1.24), rs2279420 in ANK3 (P = 0.022, OR = 0.79), rs2306402 in CTNNA3 (P = 0.024, OR = 1.18), and rs5030882 in CXXC6 (P = 0.046, OR = 1.29) in 1,160 cases and 1,389 controls. 18163421 2008