FZD4, frizzled class receptor 4, 8322

N. diseases: 239; N. variants: 28
Disease: Retinopathy of Prematurity ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs104894223
rs104894223
Entrez Id: 8322;11098
Gene Symbol: FZD4;PRSS23
FZD4;PRSS23
CUI: C0035344
Disease:
Retinopathy of Prematurity 		C 0.700 CausalMutation CLINVAR
dbSNP: rs61735303
rs61735303
Entrez Id: 8322;11098
Gene Symbol: FZD4;PRSS23
FZD4;PRSS23
CUI: C0035344
Disease:
Retinopathy of Prematurity 		0.020 GeneticVariation BEFREE Variants p.(Pro33Ser) and p.(Pro168Ser) were found to be significantly associated with ROP. 28982955 2018
dbSNP: rs61735304
rs61735304
Entrez Id: 8322;100506368
Gene Symbol: FZD4;FZD4-DT
FZD4;FZD4-DT
CUI: C0035344
Disease:
Retinopathy of Prematurity 		0.020 GeneticVariation BEFREE Variants p.(Pro33Ser) and p.(Pro168Ser) were found to be significantly associated with ROP. 28982955 2018
dbSNP: rs61735303
rs61735303
Entrez Id: 8322;11098
Gene Symbol: FZD4;PRSS23
FZD4;PRSS23
CUI: C0035344
Disease:
Retinopathy of Prematurity 		0.020 GeneticVariation BEFREE Four of the 60 patients with ROP (6.7%) have a double missense mutation P33S/P168S that was also found in the patients with FEVR. 20008721 2009
dbSNP: rs61735304
rs61735304
Entrez Id: 8322;100506368
Gene Symbol: FZD4;FZD4-DT
FZD4;FZD4-DT
CUI: C0035344
Disease:
Retinopathy of Prematurity 		0.020 GeneticVariation BEFREE Four of the 60 patients with ROP (6.7%) have a double missense mutation P33S/P168S that was also found in the patients with FEVR. 20008721 2009
dbSNP: rs61749246
rs61749246
Entrez Id: 8322;11098
Gene Symbol: FZD4;PRSS23
FZD4;PRSS23
CUI: C0035344
Disease:
Retinopathy of Prematurity 		0.010 GeneticVariation BEFREE We suggest that rs61749246:C˃A of the FZD4 gene is likely associated with the development of ROP. 29465286 2018