rs137852986
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
0.710
GeneticVariation
BEFREE
These results suggest that truncating variants in BRIP1, and in particular p.Arg798Ter , are not associated with a substantial increase in breast cancer risk.
26921362
2016
rs137852986
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.710
CausalMutation
CLINVAR
rs1292988272
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
T
0.700
GeneticVariation
CLINVAR
Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
29922827
2018
rs368796923
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.700
GeneticVariation
CLINVAR
Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
29922827
2018
rs775537066
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
CA
0.700
CausalMutation
CLINVAR
Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
29922827
2018
rs368796923
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.700
GeneticVariation
CLINVAR
Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels.
28152038
2017
rs587780228
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.700
CausalMutation
CLINVAR
Pathologic findings in breast, fallopian tube, and ovary specimens in non-BRCA hereditary breast and/or ovarian cancer syndromes: a study of 18 patients with deleterious germline mutations in RAD51C, BARD1, BRIP1, PALB2, MUTYH, or CHEK2.
28709830
2017
rs587780228
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.700
CausalMutation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
rs587780236
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
TA
0.700
CausalMutation
CLINVAR
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
27433846
2016
rs587780236
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
TA
0.700
CausalMutation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
rs587780833
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
T
0.700
GeneticVariation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
rs756853672
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.700
GeneticVariation
CLINVAR
No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing.
26921362
2016
rs775171520
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
T
0.700
CausalMutation
CLINVAR
Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer.
26824983
2016
rs775537066
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
CA
0.700
CausalMutation
CLINVAR
No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing.
26921362
2016
rs786203700
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
C
0.700
GeneticVariation
CLINVAR
Inherited Mutations in Women With Ovarian Carcinoma.
26720728
2016
rs1057519365
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.700
CausalMutation
CLINVAR
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
25058500
2015
rs1555616143
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.700
CausalMutation
CLINVAR
Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel.
25186627
2015
rs1567878148
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
TA
0.700
CausalMutation
CLINVAR
Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.
26315354
2015
rs587780833
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
T
0.700
GeneticVariation
CLINVAR
Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment.
26270727
2015
rs756853672
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.700
GeneticVariation
CLINVAR
Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.
26315354
2015
rs775537066
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
CA
0.700
CausalMutation
CLINVAR
Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.
26315354
2015
rs137852985
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force recommendation statement.
24366376
2014
rs137852985
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
0.700
GeneticVariation
UNIPROT
Summaries for patients. Assessing the genetic risk for BRCA-related breast or ovarian cancer in women: recommendations from the U.S. Preventive Services Task Force.
24366402
2014
rs1057519365
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.700
CausalMutation
CLINVAR
Mutations in BRIP1 confer high risk of ovarian cancer.
21964575
2011
rs1060501774
×
Entrez Id:
83990
Gene Symbol:
BRIP1
BRIP1
Malignant neoplasm of breast
A
0.700
GeneticVariation
CLINVAR
Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control.
21127055
2011