DGAT2, diacylglycerol O-acyltransferase 2, 84649

N. diseases: 41; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1806895
rs1806895
Entrez Id: 84649;283214
Gene Symbol: DGAT2;LOC283214
DGAT2;LOC283214
CUI: C0001948
Disease:
Alcohol consumption 		C 0.700 GeneticVariation GWASCAT Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. 30698716 2019
dbSNP: rs1806895
rs1806895
Entrez Id: 84649;283214
Gene Symbol: DGAT2;LOC283214
DGAT2;LOC283214
CUI: C0392885
Disease:
High density lipoprotein measurement 		C 0.700 GeneticVariation GWASCAT Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. 30698716 2019
dbSNP: rs72997616
rs72997616
Entrez Id: 84649;283214
Gene Symbol: DGAT2;LOC283214
DGAT2;LOC283214
CUI: C1445957
Disease:
Serum total cholesterol measurement 		A 0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs11236530
rs11236530
Entrez Id: 84649
Gene Symbol: DGAT2
DGAT2
CUI: C0428472
Disease:
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs11236530
rs11236530
Entrez Id: 84649
Gene Symbol: DGAT2
DGAT2
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs3060
rs3060
Entrez Id: 84649
Gene Symbol: DGAT2
DGAT2
CUI: C0242339
Disease:
Dyslipidemias 		0.010 GeneticVariation BEFREE This study examined the relationships of baseline phenotypes and the common polymorphisms in DGAT1 and DGAT2 with the lipid responses to niacin.Lipid responses in Chinese patients with dyslipidemia treated with the extended release (ER) niacin/laropiprant combination 1000/20 mg for 4 weeks and then 2000/40 mg for 8 weeks (n = 121, the primary study) or with ER niacin 1500 mg for at least 4 weeks (n = 68, the replication study) were analyzed according to genotypes of DGAT1 rs7003945 T>C and DGAT2 rs3060 T>C polymorphisms.Treatment with ER niacin improved all lipid parameters in both studies. 25997070 2015