RGS5, regulator of G protein signaling 5, 8490

N. diseases: 52; N. variants: 5
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs902727464
rs902727464
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0948364
Disease:
Periprosthetic osteolysis
A 0.700 GeneticVariation GWASCAT The 2018 Otto Aufranc Award: How Does Genome-wide Variation Affect Osteolysis Risk After THA? 30794219 2019
dbSNP: rs76121963
rs76121963
Entrez Id: 8490;83540
Gene Symbol: RGS5;NUF2
RGS5;NUF2
CUI: C0005890
Disease:
Body Height
T 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs1056515
rs1056515
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C1956346
Disease:
Coronary Artery Disease
0.010 GeneticVariation BEFREE Our study identifies a common variant rs1056515 as a genetic marker for CAD and rare variants in LD with rs1056515 leading to decreased expression of RGS5, which contributes to atherosclerosis by impairing endothelial cell function. 31605122 2019
dbSNP: rs1056515
rs1056515
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0004153
Disease:
Atherosclerosis
0.010 GeneticVariation BEFREE Our study identifies a common variant rs1056515 as a genetic marker for CAD and rare variants in LD with rs1056515 leading to decreased expression of RGS5, which contributes to atherosclerosis by impairing endothelial cell function. 31605122 2019
dbSNP: rs1056515
rs1056515
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0003850
Disease:
Arteriosclerosis
0.010 GeneticVariation BEFREE Our study identifies a common variant rs1056515 as a genetic marker for CAD and rare variants in LD with rs1056515 leading to decreased expression of RGS5, which contributes to atherosclerosis by impairing endothelial cell function. 31605122 2019
dbSNP: rs16849802
rs16849802
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0085580
Disease:
Essential Hypertension
0.010 GeneticVariation BEFREE The rs16849802 and haplotype GAA independently increased the risk of EH in Mongolian patients, and may be used as a risk factor for the prediction of high blood pressure. 26782409 2015
dbSNP: rs16849802
rs16849802
Entrez Id: 8490
Gene Symbol: RGS5
RGS5
CUI: C0020538
Disease:
Hypertensive disease
0.010 GeneticVariation BEFREE The rs16849802 and haplotype GAA independently increased the risk of EH in Mongolian patients, and may be used as a risk factor for the prediction of high blood pressure. 26782409 2015
dbSNP: rs2815272
rs2815272
Entrez Id: 8490;101928404
Gene Symbol: RGS5;LOC101928404
RGS5;LOC101928404
CUI: C0020538
Disease:
Hypertensive disease
0.010 GeneticVariation BEFREE The strongest signal for hypertension was for rs2815272 in the RGS5 gene (P = 9.3 × 10). 21881522 2011