NUMB, NUMB endocytic adaptor protein, 8650

N. diseases: 55; N. variants: 4
Disease: Coronary Artery Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12435797
rs12435797
Entrez Id: 8650
Gene Symbol: NUMB
NUMB
CUI: C1956346
Disease:
Coronary Artery Disease 		0.010 GeneticVariation BEFREE In addition, for the total (n = 857) and male (n = 582) Uighur Chinese, we observed that rs12435797 was associated with CAD in an additive and recessive model (P = 0.021 and P = 0.009; P = 0.048 and P = 0.034). 26415596 2015
dbSNP: rs2108552
rs2108552
Entrez Id: 8650
Gene Symbol: NUMB
NUMB
CUI: C1956346
Disease:
Coronary Artery Disease 		0.010 GeneticVariation BEFREE The results of this study indicate that CC genotype of rs2108552 and T-C-T-C haplotypes in Numb gene is a possible risk genetic marker and G allele and G-G-T-C haplotypes is a possible protective genetic marker for CAD in male Han Chinese. 26415596 2015