TNKS, tankyrase, 8658

N. diseases: 88; N. variants: 9
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs35231275
rs35231275
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0001948
Disease:
Alcohol consumption 		A 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs4383974
rs4383974
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0001948
Disease:
Alcohol consumption 		C 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs4383974
rs4383974
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0871470
Disease:
Systolic Pressure 		C 0.700 GeneticVariation GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
dbSNP: rs4840437
rs4840437
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0271183
Disease:
Severe myopia 		0.010 GeneticVariation BEFREE Among 12 SNPs, rs4840437 and rs6989782 in <i>TNKS</i> gene were found significant association with HM. 31134845 2019
dbSNP: rs6989782
rs6989782
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0271183
Disease:
Severe myopia 		0.010 GeneticVariation BEFREE Among 12 SNPs, rs4840437 and rs6989782 in <i>TNKS</i> gene were found significant association with HM. 31134845 2019
dbSNP: rs12541709
rs12541709
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma 		0.010 GeneticVariation BEFREE TNKS1 SNPs (rs11991621 rs10503380, and rs7015700) were associated with NSCLC risk, whereas rs6601328 and rs12541709 inversely associated with NSCLC or ADC risk in this Chinese population. 26617760 2015
dbSNP: rs12541709
rs12541709
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0001418
Disease:
Adenocarcinoma 		0.010 GeneticVariation BEFREE TNKS1 SNPs (rs11991621 rs10503380, and rs7015700) were associated with NSCLC risk, whereas rs6601328 and rs12541709 inversely associated with NSCLC or ADC risk in this Chinese population. 26617760 2015
dbSNP: rs7015700
rs7015700
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0001418
Disease:
Adenocarcinoma 		0.010 GeneticVariation BEFREE TNKS1 SNPs (rs11991621 rs10503380, and rs7015700) were associated with NSCLC risk, whereas rs6601328 and rs12541709 inversely associated with NSCLC or ADC risk in this Chinese population. 26617760 2015
dbSNP: rs7015700
rs7015700
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma 		0.010 GeneticVariation BEFREE TNKS1 SNPs (rs11991621 rs10503380, and rs7015700) were associated with NSCLC risk, whereas rs6601328 and rs12541709 inversely associated with NSCLC or ADC risk in this Chinese population. 26617760 2015
dbSNP: rs6990300
rs6990300
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Several TL-related single nucleotide polymorphisms had modest association with breast cancer risk overall, including TEP1 rs93886 (OR 0.82, 95% CI 0.70,0.95); TERF2 rs3785074 (OR 1.13, 95% CI 1.03,1.24); TERT rs4246742 (OR 0.85, 95% CI 0.77,0.93); TERT rs10069690 (OR 1.13, 95% CI 1.03,1.24); TERT rs2242652 (OR 1.51, 95% CI 1.11,2.04); and TNKS rs6990300 (OR 0.89, 95% CI 0.81,0.97). 23629941 2013
dbSNP: rs6990300
rs6990300
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE Several TL-related single nucleotide polymorphisms had modest association with breast cancer risk overall, including TEP1 rs93886 (OR 0.82, 95% CI 0.70,0.95); TERF2 rs3785074 (OR 1.13, 95% CI 1.03,1.24); TERT rs4246742 (OR 0.85, 95% CI 0.77,0.93); TERT rs10069690 (OR 1.13, 95% CI 1.03,1.24); TERT rs2242652 (OR 1.51, 95% CI 1.11,2.04); and TNKS rs6990300 (OR 0.89, 95% CI 0.81,0.97). 23629941 2013
dbSNP: rs6985140
rs6985140
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0684249
Disease:
Carcinoma of lung 		0.010 GeneticVariation BEFREE The TERT rs2735940 g.C > T and rs2736098 g.G > A, and TNKS1 rs6985140 g.A > G were significantly associated with the risk of lung cancer. 19773453 2009
dbSNP: rs6985140
rs6985140
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C1306460
Disease:
Primary malignant neoplasm of lung 		0.010 GeneticVariation BEFREE The TERT rs2735940 g.C > T and rs2736098 g.G > A, and TNKS1 rs6985140 g.A > G were significantly associated with the risk of lung cancer. 19773453 2009
dbSNP: rs6985140
rs6985140
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0242379
Disease:
Malignant neoplasm of lung 		0.010 GeneticVariation BEFREE The TERT rs2735940 g.C > T and rs2736098 g.G > A, and TNKS1 rs6985140 g.A > G were significantly associated with the risk of lung cancer. 19773453 2009
dbSNP: rs6990097
rs6990097
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE However, none of them was associated with BC susceptibility and only rs6990097 correlated with regional lymph node metastasis (odds ratio (OR) 1.38, 95% confidence interval (CI) 1.08-1.77). 19766477 2009
dbSNP: rs6990097
rs6990097
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE However, none of them was associated with BC susceptibility and only rs6990097 correlated with regional lymph node metastasis (odds ratio (OR) 1.38, 95% confidence interval (CI) 1.08-1.77). 19766477 2009
dbSNP: rs6990097
rs6990097
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
CUI: C0686619
Disease:
Secondary malignant neoplasm of lymph node 		0.010 GeneticVariation BEFREE However, none of them was associated with BC susceptibility and only rs6990097 correlated with regional lymph node metastasis (odds ratio (OR) 1.38, 95% confidence interval (CI) 1.08-1.77). 19766477 2009