Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11084095
rs11084095
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C0031099
Disease:
Periodontitis 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci. 30218097 2019
dbSNP: rs11084095
rs11084095
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C0600298
Disease:
Periodontosis 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci. 30218097 2019
dbSNP: rs11084096
rs11084096
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs1106476
rs1106476
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C2985280
Disease:
Blood Protein Measurement 		A 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs147859411
rs147859411
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C2985280
Disease:
Blood Protein Measurement 		TTTTTG 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs181481353
rs181481353
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C2985280
Disease:
Blood Protein Measurement 		A 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs2278832
rs2278832
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C2985280
Disease:
Blood Protein Measurement 		G 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs73050865
rs73050865
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C2985280
Disease:
Blood Protein Measurement 		G 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs74861892
rs74861892
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C2985280
Disease:
Blood Protein Measurement 		A 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs4284742
rs4284742
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C0031106
Disease:
Aggressive Periodontitis 		G 0.700 GeneticVariation GWASCAT A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis. 28449029 2017
dbSNP: rs34312547
rs34312547
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C0200635
Disease:
Lymphocyte Count measurement 		C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs10414149
rs10414149
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C0023343
Disease:
Leprosy 		A 0.700 GeneticVariation GWASCAT Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy. 25642632 2015
dbSNP: rs4284742
rs4284742
Entrez Id: 8778
Gene Symbol: SIGLEC5
SIGLEC5
CUI: C0031099
Disease:
Periodontitis 		0.010 GeneticVariation BEFREE A locus at SIGLEC5 (sialic acid binding Ig-like lectin 5) and a chromosomal region downstream of the DEFA1A3 locus (defensin alpha 1-3) showed association with both disease phenotypes and were associated with periodontitis at a genome-wide significance level in the pooled samples, with P = 1.09E-08 (rs4284742,-G; OR = 1.34, 95% CI = 1.21-1.48) and P = 5.48E-10 (rs2738058,-T; OR = 1.28, 95% CI = 1.18-1.38), respectively. 28449029 2017