rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
A recurrent mutation in KCNA2 as a novel cause of hereditary spastic paraplegia and ataxia.
27543892
2016
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Diagnostic exome sequencing provides a molecular diagnosis for a significant proportion of patients with epilepsy.
26795593
2016
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Cornelia de Lange syndrome.
25209348
2015
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
HDAC8-deficiency causes an X-linked dominant disorder with a wide range of severity.
25800122
2015
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
A new syndrome of intellectual disability with dysmorphism due to TBL1XR1 deletion.
25425123
2015
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
A girl with West syndrome and autistic features harboring a de novo TBL1XR1 mutation.
25102098
2014
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Histone deacetylase 3 is necessary for proper brain development.
25339172
2014
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR.
23770587
2013
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Histone deacetylase complexes promote trinucleotide repeat expansions.
22363205
2012
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Structure of HDAC3 bound to co-repressor and inositol tetraphosphate.
22230954
2012
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations.
22495309
2012
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Probing the role of HDACs and mechanisms of chromatin-mediated neuroplasticity.
21545841
2011
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Haploinsufficiency of HDAC4 causes brachydactyly mental retardation syndrome, with brachydactyly type E, developmental delays, and behavioral problems.
20691407
2010
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Decoding the epigenetic language of neuronal plasticity.
19109904
2008
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice.
18830415
2008
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Distribution of histone deacetylases 1-11 in the rat brain.
17416969
2007
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2.
17158926
2007
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain.
15897262
2005
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors.
15837933
2005
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells.
11742974
2001
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3.
11509652
2001
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
The histone deacetylase-3 complex contains nuclear receptor corepressors.
10860984
2000
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
N-terminal region, C-terminal region, nuclear export signal, and deacetylation activity of histone deacetylase-3 are essential for the viability of the DT40 chicken B cell line.
10748092
2000
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3.
10944117
2000
rs1554216308
×
Entrez Id:
8841
Gene Symbol:
HDAC3
HDAC3
Movement Disorders
C
0.700
GeneticVariation
CLINVAR
Cloning and characterization of the murine histone deacetylase (HDAC3).
10491319
1999