DisGeNET - a database of gene-disease associations

GPRC5A, G protein-coupled receptor class C group 5 member A, 9052

N. diseases: 90; N. variants: 5

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs12811512

Entrez Id:	9052
Gene Symbol:	GPRC5A

GPRC5A

CUI:	C0014772
Disease:

Red Blood Cell Count measurement

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs1148732

Entrez Id:	9052;693199
Gene Symbol:	GPRC5A;MIR614

GPRC5A;MIR614

CUI:	C0153536
Disease:

Malignant melanoma of skin of lower limb

0.700

GeneticVariation

GWASCAT

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.

30429480

2018

dbSNP:

rs1148732

Entrez Id:	9052;693199
Gene Symbol:	GPRC5A;MIR614

GPRC5A;MIR614

CUI:	C0151779
Disease:

Cutaneous Melanoma

0.700

GeneticVariation

GWASCAT

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.

30429480

2018

dbSNP:

rs1148732

Entrez Id:	9052;693199
Gene Symbol:	GPRC5A;MIR614

GPRC5A;MIR614

CUI:	C0153535
Disease:

Malignant melanoma of skin of upper limb

0.700

GeneticVariation

GWASCAT

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.

30429480

2018

dbSNP:

rs1640875

Entrez Id:	9052
Gene Symbol:	GPRC5A

GPRC5A

CUI:	C0153536
Disease:

Malignant melanoma of skin of lower limb

0.700

GeneticVariation

GWASCAT

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.

30429480

2018

dbSNP:

rs1640875

Entrez Id:	9052
Gene Symbol:	GPRC5A

GPRC5A

CUI:	C0153535
Disease:

Malignant melanoma of skin of upper limb

0.700

GeneticVariation

GWASCAT

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.

30429480

2018

dbSNP:

rs1640875

Entrez Id:	9052
Gene Symbol:	GPRC5A

GPRC5A

CUI:	C0151779
Disease:

Cutaneous Melanoma

0.700

GeneticVariation

GWASCAT

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.

30429480

2018

dbSNP:

rs12811512

Entrez Id:	9052
Gene Symbol:	GPRC5A

GPRC5A

CUI:	C0518015
Disease:

Hemoglobin measurement

0.700

GeneticVariation

GWASCAT

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

27863252

2016

dbSNP:

rs12811512

Entrez Id:	9052
Gene Symbol:	GPRC5A

GPRC5A

CUI:	C0018935
Disease:

Hematocrit procedure

0.700

GeneticVariation

GWASCAT

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

27863252

2016

dbSNP:

rs748582997

Entrez Id:	9052
Gene Symbol:	GPRC5A

GPRC5A

CUI:	C0152013
Disease:

Adenocarcinoma of lung (disorder)

0.010

GeneticVariation

BEFREE

All LUADs were found to harbor somatic mutations in the Kras oncogene (p. G12D or p. Q61R).

28653505

2017

dbSNP:

rs773168418

Entrez Id:	9052
Gene Symbol:	GPRC5A

GPRC5A

CUI:	C0152013
Disease:

Adenocarcinoma of lung (disorder)

0.010

GeneticVariation

BEFREE

All LUADs were found to harbor somatic mutations in the Kras oncogene (p. G12D or p. Q61R).

28653505

2017