DisGeNET - a database of gene-disease associations

NEURL1, neuralized E3 ubiquitin protein ligase 1, 9148

N. diseases: 103; N. variants: 10

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs6584555

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.740

GeneticVariation

BEFREE

We did not find significant association between SNP rs2595104 and rs6584555 andAF.

31039368

2019

dbSNP:

rs6584555

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.740

GeneticVariation

BEFREE

Significant allelic and genotypic associations were identified between NEURL variant rs6584555 and GJA1 variant rs13216675 and AF.

29459676

2018

dbSNP:

rs6584555

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.740

GeneticVariation

BEFREE

Six single-nucleotide polymorphisms-rs593479 (1q24 in PRRX1), rs1906617 (4q25 near PITX2), rs11773845 (7q31 in CAV1), rs6584555 (10q25 in NEURL), rs6490029 (12q24 in CUX2), and rs12932445 (16q22 in ZFHX3) (P < 1.9 × 10<sup>-5</sup>)-were confirmed as being associated with AF.

28129963

2017

dbSNP:

rs6584555

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.740

GeneticVariation

GWASCAT

Korean atrial fibrillation network genome-wide association study for early-onset atrial fibrillation identifies novel susceptibility loci.

28460022

2017

dbSNP:

rs6584555

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.740

GeneticVariation

BEFREE

NEURL rs6584555 and CAND2 rs4642101 contribute to postoperative atrial fibrillation: a prospective study among Chinese population.

27203392

2016

dbSNP:

rs11598047

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.700

GeneticVariation

GWASCAT

Multi-ethnic genome-wide association study for atrial fibrillation.

29892015

2018

dbSNP:

rs11598047

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.700

GeneticVariation

GWASCAT

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.

30061737

2018

dbSNP:

rs55693294

Entrez Id:	9148;102724341
Gene Symbol:	NEURL1;NEURL1-AS1

NEURL1;NEURL1-AS1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.700

GeneticVariation

GWASCAT

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.

30061737

2018

dbSNP:

rs60572254

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.700

GeneticVariation

GWASCAT

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development.

29290336

2018

dbSNP:

rs72848971

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0040420
Disease:

Tonometry

0.700

GeneticVariation

GWASCAT

Genome-wide association analyses identify new loci influencing intraocular pressure.

29617998

2018

dbSNP:

rs74154533

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C1531624
Disease:

Cardioembolic stroke

0.700

GeneticVariation

GWASCAT

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

29531354

2018

dbSNP:

rs11598047

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.700

GeneticVariation

GWASCAT

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

28416818

2017

dbSNP:

rs60572254

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.700

GeneticVariation

GWASCAT

Identification of six new genetic loci associated with atrial fibrillation in the Japanese population.

28416822

2017

dbSNP:

rs60848348

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0004238
Disease:

Atrial Fibrillation

0.700

GeneticVariation

GWASCAT

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

28416818

2017

dbSNP:

rs11597473

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0036341
Disease:

Schizophrenia

0.700

GeneticVariation

GWASCAT

Genome-wide association study of schizophrenia in Ashkenazi Jews.

26198764

2015

dbSNP:

rs11191732

Entrez Id:	9148
Gene Symbol:	NEURL1

NEURL1

CUI:	C0036341
Disease:

Schizophrenia

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies five new schizophrenia loci.

21926974

2011

dbSNP:

rs7071247

Entrez Id:	9148;102724341
Gene Symbol:	NEURL1;NEURL1-AS1

NEURL1;NEURL1-AS1

CUI:	C0032176
Disease:

Platelet aggregation

0.700

GeneticVariation

GWASDB

Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.

20526338

2010