CD28, CD28 molecule, 940

N. diseases: 364; N. variants: 11
Disease: Malignant Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3116496
rs3116496
Entrez Id: 940
Gene Symbol: CD28
CD28
CUI: C0006826
Disease:
Malignant Neoplasms 		0.030 GeneticVariation BEFREE CONCLUSIONS Our meta-analysis confirmed that rs3</span>116496 was significantly related to cancer risk, especially in an Asian population, and was strongly correlated with the increased risk of breast cancer, leukemia and colorectal cancer. 30867406 2019
dbSNP: rs3116496
rs3116496
Entrez Id: 940
Gene Symbol: CD28
CD28
CUI: C0006826
Disease:
Malignant Neoplasms 		0.030 GeneticVariation BEFREE CD28 polymorphism, rs3116496, contributes to cancer susceptibility in the case of multiple cancers. 25534869 2015
dbSNP: rs3116496
rs3116496
Entrez Id: 940
Gene Symbol: CD28
CD28
CUI: C0006826
Disease:
Malignant Neoplasms 		0.030 GeneticVariation BEFREE The results indicated that CD28 T > C polymorphism (rs3116496) was not associated with the risk of cancer in overall population (CC + CT vs. TT, OR = 1.17, 95 %CI = 0.94-1.47, P H = 0.00; CC vs. CT + TT, OR = 1.26, 95 %CI = 0.92-1.73, P H = 0.86; CC vs. TT, OR = 1.27, 95 %CI = 0.92-1.74, P H = 0.85; CT vs. TT, OR = 1.15, 95 %CI = 0.91-1.46, P H = 0.00; and C vs. T, OR = 1.17, 95 %CI = 0.97-1.41, P H = 0.00). 24927673 2014