ACYP2, acylphosphatase 2, 98

N. diseases: 42; N. variants: 20
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1682111
rs1682111
Entrez Id: 98
Gene Symbol: ACYP2
ACYP2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.020 GeneticVariation BEFREE Minor allele of rs1682111 and rs10439478 and its interaction were associated with increased BC risk. 29033240 2018
dbSNP: rs1682111
rs1682111
Entrez Id: 98
Gene Symbol: ACYP2
ACYP2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.020 GeneticVariation BEFREE In addition, we found that rs1682111 and rs17045754 were associated with the risk of BC and correlated with recurrence, and that rs6713088 correlated with tumor size. 27894080 2016
dbSNP: rs10439478
rs10439478
Entrez Id: 98
Gene Symbol: ACYP2
ACYP2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.010 GeneticVariation BEFREE Minor allele of rs1682111 and rs10439478 and its interaction were associated with increased BC risk. 29033240 2018
dbSNP: rs12621038
rs12621038
Entrez Id: 98
Gene Symbol: ACYP2
ACYP2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.010 GeneticVariation BEFREE Statistical analysis revealed that rs12621038 was associated with a decreased risk of BC in the allele (T vs. C: odds ratio [OR] = 0.71, 95% confidence interval [95% CI] = 0.52-0.94; p = 0.016), homozygous (TT vs. CC: OR = 0.47, 95% CI = 0.24-0.85; p = 0.014), dominant (OR = 0.62; 95% CI = 0.40-0.96; p = 0.032), and additive (OR = 0.68; 95% CI = 0.50-0.92; p = 0.012) models. 27894080 2016
dbSNP: rs17045754
rs17045754
Entrez Id: 98;105374610
Gene Symbol: ACYP2;LOC105374610
ACYP2;LOC105374610
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.010 GeneticVariation BEFREE In addition, we found that rs1682111 and rs17045754 were associated with the risk of BC and correlated with recurrence, and that rs6713088 correlated with tumor size. 27894080 2016
dbSNP: rs6713088
rs6713088
Entrez Id: 98
Gene Symbol: ACYP2
ACYP2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.010 GeneticVariation BEFREE In addition, we found that rs1682111 and rs17045754 were associated with the risk of BC and correlated with recurrence, and that rs6713088 correlated with tumor size. 27894080 2016
dbSNP: rs843711
rs843711
Entrez Id: 98
Gene Symbol: ACYP2
ACYP2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.010 GeneticVariation BEFREE Finally, rs843711 inversely correlated with clinical stage III/IV BC. 27458158 2016