MED12, mediator complex subunit 12, 9968

N. diseases: 340; N. variants: 21
Disease: Carcinogenesis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519912
rs1057519912
Entrez Id: 9968
Gene Symbol: MED12
MED12
CUI: C0596263
Disease:
Carcinogenesis 		0.020 GeneticVariation BEFREE To elucidate the molecular mechanisms leading to tumorigenesis in prostate cancer, we analyzed global interaction profiles of wild-type and L1224F mutant MED12 with quantitative affinity purification-mass spectrometry (AP-MS). 26383637 2016
dbSNP: rs1057519912
rs1057519912
Entrez Id: 9968
Gene Symbol: MED12
MED12
CUI: C0596263
Disease:
Carcinogenesis 		0.020 GeneticVariation BEFREE Contrary to the findings of Barbieri et al, our data indicate either that the p.L1224F mutation in the MED12 gene plays no role in prostate carcinogenesis or that this alteration is only relevant in a small subgroup of tumours. 23661306 2013