rs10033900, CFI

N. diseases: 4
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.820 GeneticVariation GWASCAT A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. 26691988 2016
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.820 GeneticVariation GWASDB Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. 22705344 2012
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.820 GeneticVariation GWASDB Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. 21665990 2012
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.820 GeneticVariation GWASCAT Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. 21665990 2012
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.820 GeneticVariation BEFREE Individuals with the homozygous CFI rs10033900 TT genotype had a 2.9 [1.2-7.2]-fold increased risk, and those with the CFH Y402H GG genotype had a 2.2 [1.0-4.8]-fold higher risk of developing AMD compared with non-carriers. 21906714 2012
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.820 GeneticVariation BEFREE There was a possible association between LIPC and complement factor H (CFH) rs1410996, and a possible interaction effect between LIPC and both CFH rs10033900 and the complement factor I (CFI) variants in terms of risk of AMD. 21139980 2011
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.820 GeneticVariation GWASDB Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). 20385826 2010
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.820 GeneticVariation GWASCAT Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). 20385826 2010
Geographic Atrophy
CUI: C1536085
Disease: Geographic Atrophy
0.700 GeneticVariation GWASCAT A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. 26691988 2016
exudative macular degeneration
CUI: C2237660
Disease: exudative macular degeneration
0.700 GeneticVariation GWASCAT A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. 26691988 2016
exudative macular degeneration
CUI: C2237660
Disease: exudative macular degeneration
0.700 GeneticVariation GWASCAT Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. 22705344 2012
Myopia
CUI: C0027092
Disease: Myopia
0.010 GeneticVariation BEFREE One SNP (rs10033900) in the CFI gene, which encodes a protein involved in the inflammatory pathway, was significantly associated with myopic CNV in multivariate analysis after correction for multiple testing. 22678500 2012