|
Sjogren's Syndrome
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23.
|
24097066 |
2013 |
|
Sjogren's Syndrome
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23.
|
24097066 |
2013 |
|
Primary biliary cirrhosis
|
|
0.710 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies six novel risk loci for primary biliary cholangitis.
|
28425483 |
2017 |
|
Primary biliary cirrhosis
|
|
0.710 |
GeneticVariation
|
BEFREE |
We detected significant associations with PBC susceptibility for several STAT4 SNPs (rs10168266; P = 9.4 × 10(-3), rs11889341; P = 1.2 × 10(-3), rs7574865; P = 4.0 × 10(-4), rs8179673; P = 2.0 × 10(-4), and rs10181656; P = 4.2 × 10(-5)).
|
24648611 |
2014 |
|
Lupus Erythematosus, Systemic
|
|
0.700 |
GeneticVariation
|
GWASDB |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation
|
GWASDB |
Functional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in Japanese.
|
23028356 |
2012 |
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation
|
GWASDB |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
|
Neuromyelitis Optica
|
|
0.010 |
GeneticVariation
|
BEFREE |
After correcting for multiple test comparisons, the minor alleles of four STAT4 SNPs exhibited significant association with increased risk of NMOSD (rs7574865 T, odds ratio [OR] = 1.66, 95% confidence interval [CI] 1.32-2.08, P <sub>corr</sub> = 0.000; rs10181656 G, OR = 1.62, 95% CI 1.29-2.03, P <sub>corr</sub> = 0.000; rs10168266 T, OR = 1.59, 95% CI 1.27-2.00, P <sub>corr</sub> = 0.001; and rs13426947 A, OR = 1.51, 95% CI 1.21-1.90, P <sub>corr</sub> = 0.004).
|
28852993 |
2017 |
|
Hepatitis B
|
|
0.010 |
GeneticVariation
|
BEFREE |
Further, haplotype-based association analysis indicated that the haplotype CTCTT, formed by SNPs rs8179673, rs7574865, rs4274624, rs11889341, and rs10168266, was significantly associated with HBV infection (OR 0.87; 95 % CI 0.76, 0.99; P = 0.022) and clearance (OR 0.86; 95 % CI 0.75, 0.99; P = 0.018).
|
27444301 |
2016 |
|
Systemic Scleroderma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The T-allele carriers of rs7574865 and rs10168266 were strongly associated with the presence of anti-topoisomerase I (ATA) and pulmonary fibrosis in SSc patients, as well as with diffuse cutaneous SSc (dcSSc).
|
23755762 |
2013 |
|
Pulmonary Fibrosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The T-allele carriers of rs7574865 and rs10168266 were strongly associated with the presence of anti-topoisomerase I (ATA) and pulmonary fibrosis in SSc patients, as well as with diffuse cutaneous SSc (dcSSc).
|
23755762 |
2013 |