The study showed a relationship between an increased BC risk under the dominant genetic model of <i>CRY2</i> rs10838524, <i>PER2</i> rs934945, and recessive genetic model of <i>PER1</i> rs2735611.
The study showed a relationship between an increased BC risk under the dominant genetic model of <i>CRY2</i> rs10838524, <i>PER2</i> rs934945, and recessive genetic model of <i>PER1</i> rs2735611.
Moreover, we found an increased risk of estrogen-/progesterone-positive tumors under the dominant genetic model of <i>PER2</i> rs934945 and estrogen negative tumors under the variant genotype of <i>CRY2</i> rs10838524, <i>PER1</i> rs2735611.
The findings that have gained support indicate that genetic variants of RORA (rs2028122) and CRY1 (rs2287161) associate with depressive disorder, those of RORB (rs7022435, rs3750420, rs1157358, rs3903529) and NR1D1 (rs2314339) with bipolar disorder, and those of NPAS2 (rs11541353) and CRY2 (rs10838524) with seasonal affective disorder or winter depression.
The findings that have gained support indicate that genetic variants of RORA (rs2028122) and CRY1 (rs2287161) associate with depressive disorder, those of RORB (rs7022435, rs3750420, rs1157358, rs3903529) and NR1D1 (rs2314339) with bipolar disorder, and those of NPAS2 (rs11541353) and CRY2 (rs10838524) with seasonal affective disorder or winter depression.