Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.020 GeneticVariation BEFREE Endothelial progenitor cells (EPCs) from subjects homozygous for the thymine allele variant at <i>NDUFC2</i>/rs11237379, which is associated with <i>NDUFC2</i> deficiency and increased stroke risk, displayed an impairment of autophagy and increased senescence in response to high salt levels. 31679456 2019
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.020 GeneticVariation BEFREE Subjects carrying TT/rs11237379 and A allele variant at NDUFC2/rs641836 had further increased risk of stroke (OR=1.56; CI, 1.14-2.13; P=0.006). 26888427 2016
Ischemic stroke
CUI: C0948008
Disease: Ischemic stroke
0.010 GeneticVariation BEFREE In humans, T allele variant at NDUFC2/rs11237379 was associated with significant reduction in gene expression and with increased occurrence of early-onset ischemic stroke by recessive mode of transmission (odds ratio [OR], 1.39; CI, 1.07-1.80; P=0.012). 26888427 2016