rs11720524, SCN5A

N. diseases: 3
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Ventricular Fibrillation
CUI: C0042510
Disease: Ventricular Fibrillation
0.010 GeneticVariation BEFREE The major C-allele of rs11720524 was present in 64% of the cases and the C/C genotype was significantly associated with VF with an odds ratio (OR) of 1.87 (95% CI: 1.12-3.12; P = 0.017). 28085969 2017
ST segment elevation myocardial infarction
CUI: C1536220
Disease: ST segment elevation myocardial infarction
0.010 GeneticVariation BEFREE Of the 27 candidate SNPs, one SNP (rs11720524) located in intron 1 of SCN5A which was previously associated with SCD was significantly associated with VF caused by first STEMI. 28085969 2017
Cardiac Arrest
CUI: C0018790
Disease: Cardiac Arrest
0.010 GeneticVariation BEFREE Four male sudden cardiac arrest survivors had intronic variant (rs11720524) in SCN5A gene. 23853484 2013