Malignant Uterine Corpus Neoplasm
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
Mammary Neoplasms
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
Nasopharyngeal Neoplasms
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
Adenocarcinoma of lung (disorder)
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
endometrial adenoacanthoma
|
|
0.700 |
GeneticVariation
|
CLINVAR |
The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors.
|
23908597 |
2013 |
endometrial adenoacanthoma
|
|
0.700 |
GeneticVariation
|
CLINVAR |
The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors.
|
23908597 |
2013 |
endometrial adenoacanthoma
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models.
|
22238366 |
2012 |
endometrial adenoacanthoma
|
|
0.700 |
GeneticVariation
|
CLINVAR |
FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor.
|
23002168 |
2012 |
endometrial adenoacanthoma
|
|
0.700 |
GeneticVariation
|
CLINVAR |
FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor.
|
23002168 |
2012 |
endometrial adenoacanthoma
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models.
|
22238366 |
2012 |
endometrial adenoacanthoma
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Drug-sensitive FGFR2 mutations in endometrial carcinoma.
|
18552176 |
2008 |
endometrial adenoacanthoma
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Drug-sensitive FGFR2 mutations in endometrial carcinoma.
|
18552176 |
2008 |
Endometrial Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
We cultured BaF3 cells overexpressing FGFR2 in high concentrations of dovitinib and identified 14 dovitinib-resistant mutations, including the N550K mutation observed in 25% of FGFR2(mutant) endometrial cancers (ECs).
|
23908597 |
2013 |
Endometrial Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
FGFR2 exons 7 and 12 unlabeled DNA probes allow for easy screening of endometrial carcinoma for the 2 most common FGFR2 mutations (S252W and N550K).
|
21285871 |
2011 |
Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
The two most common somatic mutations identified were S252W (in eight tumors) and N550K (in five samples).
|
17525745 |
2007 |