rs12344615, UBQLN1

N. diseases: 4
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.030 GeneticVariation BEFREE Several studies have reported an association between the UBQ-8i (rs12344615) polymorphism of the UBQLN1 gene and risk of Alzheimer's disease (AD), but these findings remain controversial. 25010605 2015
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.030 GeneticVariation BEFREE Allele C of rs12344615 of the UBQLN1 gene is not a risk factor for MCI or AD (OR = 0.88, CI95% 0.60-1.31 p7equal;s0.542 and OR = 0.73, CI95% 0.51-1.02 p=0.079, respectively). 22272618 2012
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.030 GeneticVariation BEFREE Our results suggest that it is unlikely that the SNP rs12344615 of the UBQLN1 gene is related to the onset of AD, PD or cognitive function. 17709205 2007
Mild cognitive disorder
CUI: C1270972
Disease: Mild cognitive disorder
0.010 GeneticVariation BEFREE Allele C of rs12344615 of the UBQLN1 gene is not a risk factor for MCI or AD (OR = 0.88, CI95% 0.60-1.31 p7equal;s0.542 and OR = 0.73, CI95% 0.51-1.02 p=0.079, respectively). 22272618 2012
Alzheimer Disease, Late Onset
CUI: C0494463
Disease: Alzheimer Disease, Late Onset
0.010 GeneticVariation BEFREE Recently, a single nucleotide polymorphism (SNP, A-->G) in intron 8 of UBQLN 1 at the rs12344615 site (UBQ-8i) on chromosome 9q22 was associated with a higher risk of late-onset Alzheimer's disease (AD). 20350585 2010
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.010 GeneticVariation BEFREE We found no significant difference in risk of AD or PD by the UBQLN1 SNP rs12344615 in our overall and stratified analyses in the Rotterdam Study. 17709205 2007