rs12435998, SEL1L

N. diseases: 4
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant Glioma
CUI: C0555198
Disease: Malignant Glioma
0.010 GeneticVariation BEFREE The SNP rs12435998 was prevalent in anaplastic and malignant gliomas, and in meningiomas of all histologic grades, but unrelated to brain tumor risks. 25948789 2015
Patent ductus arteriosus
CUI: C0013274
Disease: Patent ductus arteriosus
0.010 GeneticVariation BEFREE Our results suggest that the rs12435998 SNP in SEL1L gene plays a role in modifying age at diagnosis of PDA in Caucasian nonsmokers. 21656579 2012
PATENT DUCTUS ARTERIOSUS 1
CUI: C4282128
Disease: PATENT DUCTUS ARTERIOSUS 1
0.010 GeneticVariation BEFREE Our results suggest that the rs12435998 SNP in SEL1L gene plays a role in modifying age at diagnosis of PDA in Caucasian nonsmokers. 21656579 2012
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.010 GeneticVariation BEFREE A single-nucleotide polymorphism (SNP) rs12435998 in intron3 of SEL1L has previously been reported to be associated with susceptibility to Alzheimer's disease. 21656579 2012