Malignant neoplasm of breast
|
|
0.770 |
GeneticVariation
|
BEFREE |
Our findings indicate that the GG genotype of rs12443621 is associated with increased breast cancer risk whereas the GA and AA genotypes of rs2981582 are reduced risk in Han Chinese population.
|
26911390 |
2016 |
Malignant neoplasm of breast
|
|
0.770 |
GeneticVariation
|
BEFREE |
The study discovered for the first time that three SNPs (rs9933638, rs12443621, and rs3104746) at the TOX3/LOC643714 locus contributed to lung cancer risk, providing new evidences that lung cancer and breast cancer are linked at the molecular and genetic level to a certain extent.
|
27486757 |
2016 |
Malignant neoplasm of breast
|
|
0.770 |
GeneticVariation
|
BEFREE |
We observed that the rs3803662 C > T, rs12443621 A > G and rs8051542 C > T were all correlated with increased risk of breast cancer.
|
26239137 |
2015 |
Malignant neoplasm of breast
|
|
0.770 |
GeneticVariation
|
BEFREE |
The study results suggest that previously identified breast cancer risk susceptibility loci, rs12443621 (16q12) and rs6504950 (17q23), may influence breast cancer prognosis or comorbid conditions associated with overall survival.
|
23635555 |
2013 |
Malignant neoplasm of breast
|
|
0.770 |
GeneticVariation
|
BEFREE |
There is no significant association between TNRC9 rs12443621 and rs8051542 polymorphisms and risk of breast cancer in current literature.
|
20703937 |
2011 |
Malignant neoplasm of breast
|
|
0.770 |
GeneticVariation
|
BEFREE |
None of the three polymorphisms was significantly associated with breast cancer risk in the whole data set (P = 0.151, 0.644, and 0.737 for rs3803662, rs12443621. and rs8051542, respectively).
|
20213080 |
2010 |
Malignant neoplasm of breast
|
|
0.770 |
GeneticVariation
|
BEFREE |
Interestingly, a significant interaction was detected between rs12443621A/G and ER status on breast cancer risk in a case-only analysis (P for interaction = 0.004).
|
20213080 |
2010 |
Malignant neoplasm of breast
|
|
0.770 |
GeneticVariation
|
BEFREE |
The association with rs12443621 may provide clues as to how variation in TOX3 influences breast cancer risk.
|
19232126 |
2009 |
Malignant neoplasm of breast
|
|
0.770 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies novel breast cancer susceptibility loci.
|
17529967 |
2007 |
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
Our findings indicate that the GG genotype of rs12443621 is associated with increased breast cancer risk whereas the GA and AA genotypes of rs2981582 are reduced risk in Han Chinese population.
|
26911390 |
2016 |
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
The study discovered for the first time that three SNPs (rs9933638, rs12443621, and rs3104746) at the TOX3/LOC643714 locus contributed to lung cancer risk, providing new evidences that lung cancer and breast cancer are linked at the molecular and genetic level to a certain extent.
|
27486757 |
2016 |
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
We observed that the rs3803662 C > T, rs12443621 A > G and rs8051542 C > T were all correlated with increased risk of breast cancer.
|
26239137 |
2015 |
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
The study results suggest that previously identified breast cancer risk susceptibility loci, rs12443621 (16q12) and rs6504950 (17q23), may influence breast cancer prognosis or comorbid conditions associated with overall survival.
|
23635555 |
2013 |
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
There is no significant association between TNRC9 rs12443621 and rs8051542 polymorphisms and risk of breast cancer in current literature.
|
20703937 |
2011 |
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
None of the three polymorphisms was significantly associated with breast cancer risk in the whole data set (P = 0.151, 0.644, and 0.737 for rs3803662, rs12443621. and rs8051542, respectively).
|
20213080 |
2010 |
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
Interestingly, a significant interaction was detected between rs12443621A/G and ER status on breast cancer risk in a case-only analysis (P for interaction = 0.004).
|
20213080 |
2010 |
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
The association with rs12443621 may provide clues as to how variation in TOX3 influences breast cancer risk.
|
19232126 |
2009 |
Malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
The study discovered for the first time that three SNPs (rs9933638, rs12443621</span>, and rs3104746) at the TOX3/LOC643714 locus contributed to lung cancer risk, providing new evidences that lung cancer and breast cancer are linked at the molecular and genetic level to a certain extent.
|
27486757 |
2016 |
Primary malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
The study discovered for the first time that three SNPs (rs9933638, rs12443621</span>, and rs3104746) at the TOX3/LOC643714 locus contributed to lung cancer risk, providing new evidences that lung cancer and breast cancer are linked at the molecular and genetic level to a certain extent.
|
27486757 |
2016 |
Carcinoma of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
The study discovered for the first time that three SNPs (rs9933638, rs12443621</span>, and rs3104746) at the TOX3/LOC643714 locus contributed to lung cancer risk, providing new evidences that lung cancer and breast cancer are linked at the molecular and genetic level to a certain extent.
|
27486757 |
2016 |
Oestrogen receptor positive breast cancer
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, rs12443621 AG/GG genotypes were significantly associated with increased risk of ER positive breast cancer (OR = 1.38, 95% CI = 1.01-1.88), compared with homozygote AA.
|
20213080 |
2010 |