|
Malignant neoplasm of lung
|
|
0.710 |
GeneticVariation
|
GWASDB |
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
|
22899653 |
2012 |
|
Malignant neoplasm of lung
|
|
0.710 |
GeneticVariation
|
BEFREE |
However, we identified four novel SNPs (rs2036534C>T, rs667282C>T, rs12910984G>A, and rs6495309T>C) that were associated with significantly increased lung cancer risk and smoking behavior, which were all confirmed in the replication analyses [odds ratios (95% confidence intervals) in the dominant model: 1.39 (1.23-1.57; P = 2.3 x 10(-7)), 1.52 (1.35-1.71; P = 2.0 x 10(-12)), 1.44 (1.28-1.63; P = 2.7 x 10(-9)), and 1.43 (1.27-1.61; P = 2.6 x 10(-9)), respectively].
|
19491260 |
2009 |
|
Malignant neoplasm of lung
|
|
0.710 |
GeneticVariation
|
GWASDB |
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.
|
19654303 |
2009 |
|
Forced expiratory volume function
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
|
26634245 |
2015 |
|
Smoking Behaviors
|
|
0.700 |
GeneticVariation
|
GWASDB |
Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
|
20418889 |
2010 |
|
Smoking Behaviors
|
|
0.700 |
GeneticVariation
|
GWASDB |
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
|
20418888 |
2010 |
|
Smoking Behaviors
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analyses identify multiple loci associated with smoking behavior.
|
20418890 |
2010 |
|
Adenocarcinoma of lung (disorder)
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
|
19836008 |
2009 |
|
Lung Diseases, Obstructive
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two single-nucleotide polymorphisms (SNPs) in CHRNA3 (rs660652 and rs12910984) were genotyped in 219 COPD subjects registered in the Korean Obstructive Lung Disease cohort study and in 305 control subjects.
|
23207642 |
2013 |
|
Chronic Obstructive Airway Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
This case-control analysis of 219 COPD patients and 305 control participants identified a significant association between an SNP of CHRNA3 (rs12910984) and COPD (p = 0.049).
|
23207642 |
2013 |
|
Primary malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, we identified four novel SNPs (rs2036534C>T, rs667282C>T, rs12910984G>A, and rs6495309T>C) that were associated with significantly increased lung cancer risk and smoking behavior, which were all confirmed in the replication analyses [odds ratios (95% confidence intervals) in the dominant model: 1.39 (1.23-1.57; P = 2.3 x 10(-7)), 1.52 (1.35-1.71; P = 2.0 x 10(-12)), 1.44 (1.28-1.63; P = 2.7 x 10(-9)), and 1.43 (1.27-1.61; P = 2.6 x 10(-9)), respectively].
|
19491260 |
2009 |
|
Carcinoma of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, we identified four novel SNPs (rs2036534C>T, rs667282C>T, rs12910984G>A, and rs6495309T>C) that were associated with significantly increased lung cancer risk and smoking behavior, which were all confirmed in the replication analyses [odds ratios (95% confidence intervals) in the dominant model: 1.39 (1.23-1.57; P = 2.3 x 10(-7)), 1.52 (1.35-1.71; P = 2.0 x 10(-12)), 1.44 (1.28-1.63; P = 2.7 x 10(-9)), and 1.43 (1.27-1.61; P = 2.6 x 10(-9)), respectively].
|
19491260 |
2009 |